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Chlamydia Antibody, Serum (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that may indicate past or current infection with *Chlamydia trachomatis*, a common sexually transmitted bacterium. It helps determine if you’ve been exposed to the infection, even if symptoms haven’t appeared yet.

Quick summary

["This test can help identify past or current chlamydia infection, even when symptoms are absent."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111420-6
Short code
CHLSPAB
Synonyms
Chlamydia Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube without anticoagulant
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) or Immunofluorescence Assay (IFA)
CPT
86631
SNOMED
108879003
Specimen volume
1-2 mL of serum (minimum 0.5 mL)
Stability
Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of chlamydia—such as unusual discharge, pain during urination, or pelvic pain—or if you’re at higher risk for infection, such as through sexual contact with someone who has it. It’s also part of routine screening for sexually active individuals, especially those with multiple partners.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample from a vein in your arm, similar to other blood tests. The process takes a few minutes, and you can return to your normal activities afterward.

What the Test Results Mean

A positive result means your blood contains antibodies against chlamydia, suggesting past or current infection. A negative result means no detectable antibodies were found in this sample. Follow-up testing or additional questions may be needed if symptoms persist or if you’re at ongoing risk.

What Happens Next

If your test is positive, your provider will discuss next steps, which may include treatment (often with antibiotics) and follow-up testing. If negative, they may recommend retesting if you’re at ongoing risk or have symptoms.

Reference range

Negative: <1:64 titer. Positive: ≥1:64 titer or as reported by the performing laboratory based on the assay-specific cutoff.N/A

Specimen: serum

No special patient preparation required. Fasting is not necessary. Patients should inform their healthcare provider of any current antibiotic therapy, as it may affect antibody response and interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chlamydia Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result indicates your body has detected chlamydia antibodies, which could mean you’ve had an infection in the past or are currently infected. Chlamydia can cause serious health issues, including pelvic inflammatory disease (PID) in women, infertility, or long-term complications if untreated. Early treatment is key to preventing these problems.
What does a negative result mean?
A negative result means no chlamydia antibodies were found in this sample. However, it’s possible you were infected at an earlier time or the test may not have detected the infection if it was very recent. If you have symptoms or are at risk, your provider may recommend retesting or other diagnostic tests.
Can this test detect active chlamydia infection?
This test primarily detects antibodies, not the live bacterium itself. While it can indicate past or current infection, it’s not always definitive for active infection in all cases. Your provider may use additional tests (like nucleic acid amplification tests) to confirm active infection if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy