Chlamydia Genital Tract Infection Detection by Genomic Testing (Nucleic Acid Amplification)
This test checks for the presence of *Chlamydia trachomatis*—a common bacterial infection that can affect the genital area, causing symptoms like unusual discharge, pain during urination, or bleeding. It uses genetic material from the bacteria to detect infection, often done as part of routine screening or when symptoms suggest infection.
["Detects genital chlamydia infection using genetic testing, crucial for early treatment and preventing complications."]
Key facts at a glance
- LOINC
- 109710-4
- Short code
- CHLAG
- Synonyms
- Chlamydia Ag Msmt Genital
- Category
- chemistry
- Sample
- serum
- Container
- Genital specimen collection swab in transport medium (e.g., Dacron or flocked swab in Chlamydia transport medium or viral transport medium)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–99 years
- Method
- Immunochromatographic assay / Enzyme immunoassay (EIA) for direct detection of Chlamydia species antigen
- CPT
- 87320
- SNOMED
- 10828004
- Specimen volume
- One swab specimen (endocervical, urethral, or vaginal) placed in appropriate transport medium
- Stability
- Room temperature: 2 hours; Refrigerated (2-8°C): 24-48 hours; Frozen (-70°C or below): 1-2 weeks. Refer to specific transport medium manufacturer instructions for optimal stability.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms of chlamydia—such as discharge, burning during urination, or pelvic pain—or if you’re at higher risk, like having multiple sexual partners or a history of STIs. It’s also part of routine screening for sexually active individuals under certain guidelines.
How the Test Works
The test collects a sample from the genital area (e.g., cervix, urethra, or rectum) and analyzes its DNA for *Chlamydia trachomatis*. Unlike traditional cultures or antibody tests, this method detects the bacteria’s genetic material directly, often providing results in days.
What to Expect Before the Test
No special preparation is needed, but avoid sexual activity for 24–48 hours before testing to ensure an accurate sample. If you’re pregnant, inform your provider, as some treatments require special care.
What to Expect During the Test
The sample is collected using a small swab or brush, which is inserted into the genital area. It’s quick and painless, similar to a Pap smear. The sample is then sent to a lab for testing.
Reference range
Negative: No Chlamydia species antigen detected. Positive: Chlamydia species antigen detected, indicating active or recent infection.N/A
Patient should abstain from urination for at least 1 hour prior to collection of urethral specimens. For cervical/endocervical specimens, avoid douching, intercourse, or use of intravaginal medications for 24-48 hours before collection. Do not use lubricants during specimen collection as they may interfere with test performance.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Untreated chlamydia can lead to serious health issues, including pelvic inflammatory disease (PID), infertility, or chronic pelvic pain in women, and epididymitis or infertility in men. Early detection and treatment with antibiotics can prevent these complications and reduce the risk of spreading the infection to others.
Short name
Genital Chlamydia Test
Frequently asked questions
How soon will I get my results?
What does a positive result mean?
What if I have a negative result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy