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Chlamydia nucleic acid test by nucleic acid amplification (specimen: stool)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Chlamydia trachomatis*, a common bacterial infection that can affect the reproductive system, eyes, or respiratory tract. It’s used to diagnose infections in stool samples, often in cases of suspected gastrointestinal or systemic chlamydia.

Quick summary

["A stool-based test to check for *Chlamydia* bacteria, useful for diagnosing infections linked to gastrointestinal or systemic symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31767-7
Short code
Chlamydia Ag Spec Ql
Synonyms
Chlamydia Ag Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
87110
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, abdominal pain, fever, or unexplained weight loss—especially if you’ve had recent contact with someone infected. It’s also used in screening for chlamydia in stool samples, particularly in patients with suspected gastrointestinal chlamydia (e.g., after travel, exposure to contaminated water, or certain medical conditions).

How the Test Works

The test uses a specialized lab technique to identify genetic material (nucleic acids) from *Chlamydia* in your stool. This process is highly sensitive and can detect even small amounts of the bacteria’s DNA or RNA, helping confirm an infection before symptoms appear.

Sample Collection and Preparation

A stool sample is collected in a sterile container, typically during a routine bowel movement. The sample is then sent to a lab where it’s processed to extract genetic material for testing. No special preparation is needed, but avoid using laxatives or enemas before collection if instructed.

What to Expect After Testing

Results are usually available within 24–72 hours. If positive, follow-up care (e.g., antibiotics) will be recommended by your provider. If negative but symptoms persist, further testing or evaluation may be needed to rule out other causes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chlamydia Stool NAAT

Frequently asked questions

Chlamydia infections in the gastrointestinal tract can cause inflammation, chronic diarrhea, or complications like intestinal strictures. Early detection through stool testing helps prevent long-term damage and guides appropriate treatment to clear the infection.
This test is not typically used for routine sexually transmitted infection (STI) screening but is critical for diagnosing chlamydia in stool-related symptoms or specific clinical scenarios (e.g., travel-related exposure).
How accurate is this test?
This test is highly accurate for detecting *Chlamydia* in stool samples, with a sensitivity and specificity close to 95% when performed correctly. However, false negatives may occur if the sample isn’t collected properly or if the infection is very recent. Always discuss results with your provider.
Can I take antibiotics before the test?
No, antibiotics can interfere with the test results. If you suspect a chlamydia infection, avoid antibiotics until you’ve received test instructions from your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy