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Chlamydia DNA Detection by Nucleic Acid Amplification (NAA) with Probe-Based Assay (e.g., Real-Time PCR)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Chlamydia*, a common bacterial infection that can affect the reproductive system, throat, or eyes. Early detection helps prevent complications like pelvic inflammatory disease or infertility.

Quick summary

["A quick, highly sensitive test to detect *Chlamydia* infection using genetic material from the bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35729-3
Short code
Chlamydia DNA Spec Ql NAA+probe
Synonyms
Chlamydia DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87110
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Used

Healthcare providers may order this test if you have symptoms like unusual discharge, pain during urination, or if you’ve been sexually active with multiple partners. It’s also recommended as part of routine screening for sexually active individuals, especially those with multiple partners or a history of STIs.

How the Test Works

The test collects a sample (usually from the cervix, urethra, or throat) and analyzes it for *Chlamydia* genetic material using a probe-based nucleic acid amplification method. This method is highly sensitive and can detect even small amounts of the bacteria’s DNA.

Sample Collection

You’ll likely receive a swab or other collection device during a medical exam or visit. The sample is sent to a lab, where it’s processed and tested for *Chlamydia* DNA. Results are typically available within 1–3 business days.

What to Expect After Testing

If you’re tested as part of a routine screening, you may not need follow-up actions unless your results are abnormal. If you’re tested due to symptoms, your healthcare provider will discuss next steps, which may include treatment or further testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Chlamydia NAAT (Nucleic Acid Amplification Test)

Frequently asked questions

Can I get treatment while waiting for results?
Yes, if you suspect you have *Chlamydia* based on symptoms, you can start treatment immediately. Antibiotics can clear the infection, but you should still get tested to confirm the diagnosis before starting treatment.
What if my test is positive?
If your test is positive, you’ll need to complete a full course of antibiotics prescribed by your healthcare provider. Both you and your sexual partners should be treated to prevent reinfection or spreading the infection. Follow-up testing may be recommended to confirm the infection is cleared.
Is this test covered by insurance?
Most insurance plans cover routine *Chlamydia* screening for sexually active individuals under certain age or risk criteria. Check with your insurance provider for specifics, as coverage may vary. If you’re not covered, ask your healthcare provider about affordable or sliding-scale testing options.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy