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Chlamydia trachomatis nucleic acid detection in stool (qualitative probe)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Chlamydia trachomatis*, a common bacterial infection that can affect the intestines and other parts of the body. It helps identify infections that may require treatment.

Quick summary

["A simple stool test to detect a bacterial infection that can cause digestive symptoms or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35721-0
Short code
Chlamydia rRNA Anal Ql Probe
Synonyms
Chlamydia rRNA Anal Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, stomach pain, or unexplained weight loss. It’s also used in screening for gastrointestinal infections, especially in certain high-risk groups.

How the Test Works

The test uses a molecular probe to detect genetic material (nucleic acids) from *Chlamydia trachomatis* in your stool sample. If the bacteria are present, the probe will bind to their DNA, confirming an infection.

Sample Collection and Preparation

You’ll need to provide a fresh stool sample (usually collected in a special container). The sample is then analyzed in a lab using a rapid molecular method to detect the bacteria’s genetic material.

What to Expect After the Test

Results are typically available within 24–48 hours. If positive, follow your provider’s guidance for treatment (often antibiotics). If negative, further evaluation may be needed to rule out other causes of symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chlamydia Stool Probe

Frequently asked questions

This test is crucial for diagnosing gastrointestinal infections caused by *Chlamydia trachomatis*, which can lead to complications like chronic diarrhea, malnutrition, or even systemic infections if untreated. Early detection allows for prompt treatment to prevent complications.
This test is not typically used for routine screening unless symptoms suggest an infection. It’s often ordered in specific clinical scenarios, such as after exposure to the bacteria or in patients with persistent gastrointestinal symptoms.
What does a positive result mean?
A positive result indicates the presence of *Chlamydia trachomatis* genetic material in your stool, suggesting an active infection. Treatment with appropriate antibiotics is usually recommended to clear the infection and prevent complications.
Can I eat or drink before the test?
Yes, you can eat and drink normally before providing the stool sample. Avoid using laxatives or stool softeners unless instructed by your provider, as they may interfere with the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy