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Chlamydia trachomatis Nucleic Acid Detection by Probe-Based Assay (Stool)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Chlamydia trachomatis*, a common bacterial infection that can affect the reproductive system, throat, or eyes. It uses a stool sample to detect the infection, often done if symptoms like diarrhea, abdominal pain, or unexplained fever are present.

Quick summary

["This test helps identify *Chlamydia* infection in stool, guiding treatment and preventing spread."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35723-6
Short code
Chlamydia rRNA Ser Ql Probe
Synonyms
Chlamydia rRNA Ser Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
CPT
87110
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test helps your healthcare provider check for a specific health condition by measuring certain markers in your body. The results can support a diagnosis, guide treatment decisions, or help monitor how well a current treatment is working for you.

Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, unexplained abdominal pain, or fever—especially if you’ve recently traveled to areas with higher infection rates or have been exposed to someone with a gastrointestinal infection. It’s also used in research or specialized diagnostic settings where stool-based testing is preferred.

The test analyzes a small sample taken from your body using laboratory methods that detect or measure specific substances. Trained laboratory professionals process the sample, and the measurements are compared with established reference ranges to help interpret your results.

The test detects genetic material (nucleic acids) from *Chlamydia trachomatis* using a specialized probe in your stool sample. If the bacteria are present, the probe binds to their genetic material, confirming infection. This method is highly sensitive and doesn’t rely on growing the bacteria in a lab.

A trained healthcare professional will collect your sample, usually during a quick visit. Depending on the type of test, the sample may be a small amount of blood, urine, or a swab from a specific area. The collection process is generally fast, and most people find it only mildly uncomfortable, if at all.

A stool sample is collected, usually via a simple rectal swab or stool collection kit provided by your provider. The sample is then sent to a lab for processing. You may need to follow specific instructions to ensure the sample is fresh and representative.

After your sample is collected, it is sent to a laboratory for analysis, and results are typically available within a few days, though timing can vary. Your healthcare provider will contact you to discuss the results, explain what they mean, and outline any next steps, such as additional testing or treatment, if needed.

Results are typically available within 24–72 hours. If the test is positive, you’ll likely need antibiotics to treat the infection. Follow-up testing may be recommended to confirm treatment success or monitor for recurrence.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chlamydia Stool Probe Test

Frequently asked questions

If the test is positive, you may have an infection that requires treatment to prevent complications like chronic diarrhea, intestinal inflammation, or, in rare cases, long-term gastrointestinal issues. Early detection helps manage symptoms and reduces transmission risk to others.
A positive result means the test detected the substance or condition it was designed to find. Your healthcare provider will review the result together with your symptoms and medical history to decide whether confirmatory testing, treatment, or ongoing monitoring is needed.
A positive result indicates the presence of *Chlamydia trachomatis* genetic material in your stool, suggesting an active infection. This does not always mean you have symptoms, so even if you feel well, treatment may still be necessary to prevent complications or spread the infection.
It depends on the type of test being performed. Some tests require fasting for a certain number of hours beforehand, while others do not. Follow the preparation instructions provided by your healthcare provider, and ask them if you are unsure whether food or beverages are allowed.
Yes, you can eat and drink normally before the test unless your provider gives specific instructions. Avoid using laxatives or stool softeners unless directed, as they may alter the sample.
Antibiotics typically take 1–2 weeks to fully clear the infection. You may resume normal activities once you’ve completed the full course of treatment, but avoid close contact with others until advised by your provider to prevent spreading the infection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy