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Chlamydia trachomatis nucleic acid detection in stool by probe-based molecular assay

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Chlamydia trachomatis*, a common bacterial infection that can affect the reproductive system, throat, or gastrointestinal tract. It helps diagnose infections that may not cause obvious symptoms.

Quick summary

["A simple stool test to detect a bacterial infection that can cause discomfort or complications if untreated."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35728-5
Short code
Chlamydia rRNA Urth Ql Probe
Synonyms
Chlamydia rRNA Urth Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
CPT
87110
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like abdominal pain, diarrhea, or unexplained rectal discharge, or if you’ve been exposed to *Chlamydia*. It’s also used in screening for sexually transmitted infections (STIs) or after certain medical procedures. Some infections may not show symptoms, so testing can help catch them early.

How the Test Works

A small sample of your stool is collected and analyzed using a probe-based molecular test. This method detects the genetic material of *Chlamydia* with high accuracy, even if the infection is mild or in early stages. Results are typically available within 1–3 business days.

What to Expect Before the Test

No special preparation is needed. You may collect the stool sample at home or during a clinic visit. If done at home, follow the instructions provided to ensure accuracy. Avoid using laxatives or certain medications that could alter the sample.

What to Expect After the Test

After testing, you’ll receive results from your healthcare provider. If the test is positive, follow-up care (such as antibiotics) will be recommended. If negative, further evaluation may be needed if symptoms persist or exposure is suspected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Chlamydia stool PCR (Screen/Confirm)

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of *Chlamydia trachomatis* genetic material in your stool. This means you likely have an infection that requires medical treatment with antibiotics. Your provider will guide you on next steps, such as treatment and follow-up care.
What if I have mild or no symptoms?
Even if you don’t notice symptoms, *Chlamydia* can still be present. Testing is crucial because untreated infections can cause long-term health issues. If you’ve been exposed or are at higher risk, this test helps identify the infection early so it can be treated promptly.
Can I treat this at home?
No, this test is for diagnostic purposes only. If you test positive, you’ll need to see a healthcare provider for prescribed antibiotics. Avoid self-treating without medical guidance, as incorrect treatment could worsen the infection or lead to resistance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy