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Chlorideamnscnc

Published: July 31, 2026Updated: August 16, 2026

This test measures the chloride level in the amniotic fluid that surrounds the baby during pregnancy.

Quick summary

{"A simple test that checks chloride levels in the amniotic fluid","Helps doctors assess fetal lung maturity and overall pregnancy health","Performed through amniocentesis, a safe procedure guided by ultrasound","Results help monitor fetal development and detect potential complications","Normal levels vary throughout pregnancy and are interpreted by your healthcare provider"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2068-5
Short code
Chloride Amn-sCnc
Synonyms
Chloride Amn-sCnc
Category
electrolyte
Sample
fluid
Container
Sterile tube
Units
not specified
Ref low
100
Ref high
110
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82435
SNOMED
110743000
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What is this test?

The amniotic fluid chloride test measures the concentration of chloride, an important electrolyte, in the amniotic fluid. Amniotic fluid is the clear, slightly yellowish liquid that surrounds and protects the baby (fetus) inside the uterus during pregnancy. This test is part of a group of tests called amniotic fluid analysis.

Why is it performed?

This test is primarily performed to assess fetal lung maturity. As the baby develops, the lungs produce a substance called surfactant, which helps the lungs expand properly after birth. The chloride levels in amniotic fluid change as the fetal lungs mature - they tend to decrease as the lungs become more developed. This information helps healthcare providers determine if the baby's lungs are ready for birth.

How is the sample collected?

The sample is collected through a procedure called amniocentesis. During this procedure: 1) An ultrasound is used to locate the baby and the pocket of amniotic fluid; 2) A thin needle is inserted through the abdomen into the uterus; 3) A small amount of amniotic fluid is withdrawn; 4) The procedure typically takes only a few minutes. While amniocentesis is generally safe, it carries a small risk of complications, which your doctor will discuss with you.

What do the results mean?

Chloride levels in amniotic fluid change throughout pregnancy. Higher chloride levels may indicate less mature fetal lungs, while lower levels often suggest more advanced lung development. Your doctor will interpret your results in combination with other tests and your specific pregnancy situation. It's important to remember that each pregnancy is unique, and your healthcare provider will explain what the results mean for you and your baby.

Reference range

100-110 mmol/L (varies with gestational age)not specified

Specimen: fluid

Specimen obtained by amniocentesis; no fasting or special dietary prep required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is the amniotic fluid chloride test safe?
The test involves amniocentesis, which carries a small risk of complications such as infection, bleeding, or preterm labor. The procedure is performed under ultrasound guidance to minimize risks. The actual risk of serious complications is low (less than 1%), and your healthcare team will take all necessary precautions.
Does this test tell me if my baby is healthy?
This test specifically evaluates fetal lung maturity and provides information about fetal development. While it is an important tool, it is just one of many assessments used to monitor pregnancy health. Your doctor will consider multiple factors and tests to get a complete picture of your baby's wellbeing.
Will I need to prepare anything before the test?
Your healthcare provider will give you specific instructions. Generally, you may be asked to come with a full bladder for better ultrasound visualization. It's helpful to discuss any concerns or medical conditions with your doctor before the procedure.
How long does it take to get results?
Results typically take a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results and explain what they mean for your pregnancy care plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy