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Lipid Panel (Cholesterol Test)

Published: July 31, 2026Updated: August 16, 2026

A test that measures chloride levels in the cerebrospinal fluid surrounding the brain and spinal cord.

Quick summary

{"Measures chloride concentration in cerebrospinal fluid (CSF)","Helps diagnose and distinguish types of meningitis","Sample collected via lumbar puncture (spinal tap)","Normal CSF chloride: 118-132 mEq/L","Low levels may indicate tuberculous or bacterial meningitis"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2070-1
Short code
CSF Cl
Synonyms
Chloride CSF-sCnc
Category
electrolyte
Sample
csf
Container
Sterile CSF collection tube (plain polypropylene tube)
Units
not specified
Ref low
118
Ref high
132
Critical range
100 not specified – 150 not specified
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Ion-selective electrode (ISE)
CPT
82436
SNOMED
309153006
Specimen volume
1-2 mL CSF minimum; 2-4 mL preferred for multiple tests
Stability
Room temperature: 2-4 hours; Refrigerated (2-8°C): 24-48 hours; Frozen (-20°C): several weeks. Avoid repeated freeze-thaw cycles.
Hemolysis max
200
TAT
1–4 hours
Order
routine

This test measures the levels of cholesterol and triglycerides in your blood. It helps assess your risk of heart disease and stroke by evaluating the fats circulating in your bloodstream.

The CSF Chloride test measures the amount of chloride (a type of electrolyte) in your cerebrospinal fluid. CSF is the clear, protective fluid that surrounds your brain and spinal cord. Chloride helps maintain the body's fluid balance and works with other electrolytes to keep your body's systems functioning properly.

A blood sample is taken from a vein in your arm, usually after you have fasted for 9 to 12 hours. The blood is collected in a sterile tube and sent to a laboratory for analysis.

The sample is collected through a procedure called a lumbar puncture, also known as a spinal tap. During this procedure, a healthcare provider inserts a thin needle between the bones in your lower spine to draw out a small amount of cerebrospinal fluid. The area will be numbed with local anesthetic to minimize discomfort.

This test is performed to evaluate your risk of cardiovascular disease, monitor the effectiveness of cholesterol-lowering medications, and screen for lipid disorders that may require lifestyle changes or treatment.

This test is primarily used to help diagnose and differentiate between various types of meningitis (infection of the membranes surrounding the brain). It can also help evaluate other conditions affecting the brain and nervous system, such as certain metabolic or inflammatory disorders.

The results show levels of total cholesterol, LDL (bad) cholesterol, HDL (good) cholesterol, and triglycerides. High levels may indicate an increased risk of heart problems, while desirable levels are generally associated with better heart health.

Normal CSF chloride levels are typically between 118-132 mEq/L (milliequivalents per liter), which is generally higher than blood chloride levels. Your doctor will interpret your results based on your specific situation and other test findings.

Reference range

118-132 mmol/Lnot specified

Specimen: csf

No special preparation required; specimen obtained by lumbar puncture

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Decreased CSF chloride levels may indicate tuberculous meningitis (TB meningitis), bacterial meningitis, or certain metabolic conditions. Significantly low levels, especially when combined with low glucose and high protein in CSF, strongly suggest tuberculous meningitis. In viral meningitis, chloride levels are usually normal or only slightly reduced.

This test is often performed alongside other CSF tests—including glucose, protein, and cell count—to provide a complete picture of what may be affecting the brain or nervous system. The combination of findings helps doctors determine the most likely cause of your symptoms and guide appropriate treatment.

Frequently asked questions

Is the lumbar puncture procedure painful?
The area is numbed with local anesthetic, so you may feel some pressure or a brief sting during the injection. The actual needle insertion is usually not painful, though you may feel some discomfort or backache afterward. The procedure typically takes only a few minutes.
How long does it take to get results?
Results are usually available within a few hours to a couple of days, depending on the laboratory. Your healthcare provider will contact you with the results and explain what they mean for your specific case.
Are there any risks associated with this test?
Lumbar puncture is generally safe, but rare risks include headache (often called a spinal headache), back pain, bleeding, or infection at the puncture site. Very rarely, there may be nerve injury. Your healthcare provider will discuss these risks with you before the procedure.
Do I need to fast before this test?
No fasting is typically required for this test. However, always follow any specific instructions given by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy