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Chloridesalscnc

Published: July 31, 2026Updated: August 16, 2026

A test that measures the amount of chloride in your saliva to help evaluate electrolyte balance and certain gland functions.

Quick summary

{"Measures chloride levels in saliva (oral fluid)","Helps evaluate salivary gland function and electrolyte balance","Sample is collected by spitting into a container","May be used to diagnose conditions affecting saliva composition","No special preparation is typically required"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2074-3
Short code
CLSAL
Synonyms
Chloride Sal-sCnc
Category
electrolyte
Sample
serum
Container
Sterile saliva collection device (e.g., Salimetrics oral swab, dental roll, or sterile container)
Units
not specified
Ref low
10
Ref high
30
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Ion-selective electrode (ISE) or indirect potentiometry
CPT
82436
SNOMED
271295006
Specimen volume
1-2 mL of whole saliva
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is this test?

The Saliva Chloride test measures the concentration of chloride, an important electrolyte, in your saliva. Chloride is a mineral that helps maintain fluid balance, aids in digestion, and supports proper nerve and muscle function. This test evaluates how well your salivary glands are working and can provide information about your overall electrolyte status.

How is the sample collected?

For this test, you will be asked to provide a saliva sample. This is usually done by spitting into a special container. You may be asked to avoid eating, drinking, or brushing your teeth for a certain period before the test. The sample is then sent to a laboratory for analysis.

Why might I need this test?

Your healthcare provider may order this test if you have symptoms related to salivary gland problems, such as dry mouth, difficulty swallowing, or abnormal taste. It may also be used to monitor conditions that affect electrolyte balance or to evaluate the function of salivary glands.

Understanding your results

Normal chloride levels in saliva can vary depending on the laboratory and the specific methods used. Your healthcare provider will interpret your results based on your overall health, symptoms, and other test findings. Abnormal results may indicate issues with salivary gland function, dehydration, or other electrolyte imbalances.

Reference range

10-30 mmol/Lnot specified

Specimen: serum

Avoid eating, drinking, smoking, chewing gum, or oral hygiene for 30-60 min prior; rinse mouth with water before collection

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Does the test require fasting?
Your healthcare provider may ask you to fast (not eat or drink) for a specific period before the test, typically 1-2 hours. Follow any instructions provided by your doctor or the testing facility.
Is the test painful?
No, providing a saliva sample is completely painless. You simply spit into a collection container.
How long does it take to get results?
Results are typically available within a few days, but this may vary depending on the laboratory. Your healthcare provider will contact you with the results.
What can affect my saliva chloride levels?
Several factors can influence test results, including recent eating or drinking, certain medications, hydration status, smoking, and oral hygiene products. It's important to follow pre-test instructions carefully.
Do I need to do anything special to prepare?
Your provider may ask you to rinse your mouth with water before providing the sample, avoid certain foods or beverages, and refrain from using mouthwash or brushing your teeth shortly before the test. Follow all specific instructions given to you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy