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Understanding Your Blood Test: A Patient's Guide

Published: July 31, 2026Updated: August 10, 2026

A stool test that measures chloride levels to help diagnose certain digestive and genetic conditions.

Quick summary

{"Measures chloride (a salt mineral) in your stool sample","Helps doctors evaluate digestive system function","May assist in diagnosing conditions like cystic fibrosis or secretory diarrhea","Sample is collected from a routine stool specimen","Results help determine if chloride absorption or secretion is abnormal"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
2076-8
Short code
CLST
Synonyms
Chloride Stl-sCnt
Category
electrolyte
Sample
stool
Container
Clean, dry, wide-mouthed container or stool collection kit
Units
not specified
Ref low
10
Ref high
20
Critical range
— – 90 not specified
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Ion-selective electrode (ISE) or colorimetric assay
CPT
82436
SNOMED
271259006
Specimen volume
Approximately 5-10 grams of stool
Stability
Refrigerate at 2-8°C if analysis within 24 hours; freeze at -20°C for longer storage
TAT
24–72 hours
Order
routine

This test is a common blood test that checks several components of your blood to help evaluate your overall health. It measures things like red and white blood cells, hemoglobin, and platelets, and can also include a metabolic panel that checks glucose, calcium, and electrolyte levels, as well as kidney and liver function.

The stool chloride test measures the amount of chloride, an important electrolyte and salt, in your stool. Chloride plays a vital role in maintaining the body's fluid balance and is involved in digestive processes. This test helps doctors understand how your intestines are handling chloride and whether there are any abnormalities in chloride absorption or secretion.

You might need this test to check for a variety of conditions, such as anemia, infection, diabetes, or kidney and liver disease. It is often done as part of a routine physical exam, to monitor a chronic condition, or to evaluate symptoms like fatigue, weight loss, or fever.

Your doctor may order a stool chloride test if you have symptoms such as chronic diarrhea, unexplained weight loss, or signs of a digestive disorder. It may also be used to help diagnose or monitor conditions like cystic fibrosis, secretory diarrhea, or certain intestinal diseases that affect how your body processes electrolytes.

For this test, a healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood is collected in a tube and sent to a laboratory for analysis. The procedure usually takes just a few minutes, and you might feel a quick sting when the needle is inserted.

You will be given a special container to collect a small sample of stool. It's important to follow your healthcare provider's instructions carefully, which may include avoiding certain foods or medications before collection. The sample should be collected during a bowel movement and transported to the laboratory as directed.

The results of this test give your healthcare provider important information about your health. Abnormal levels of certain components can indicate various medical conditions, so your provider will discuss any out-of-range results with you and may recommend further testing or treatment. It's important to remember that normal ranges can vary based on age, sex, and other factors, so your provider will interpret the results in the context of your overall health.

Normal stool chloride levels vary by laboratory. Elevated stool chloride may indicate conditions such as secretory diarrhea, cystic fibrosis, or certain malabsorption disorders. Low chloride levels are less common but may occur in some digestive conditions. Your doctor will interpret your results in context with your symptoms and other test results.

Reference range

<20 mmol/Lnot specified

Specimen: stool

No fasting required; collect fresh liquid/unformed stool specimen (avoid recent laxatives or contrast)

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this the same as a sweat chloride test for cystic fibrosis?
No, these are different tests. The sweat chloride test is the standard test for diagnosing cystic fibrosis and measures chloride in sweat. The stool chloride test measures chloride in stool and may provide additional information but is not used as the primary screening tool for cystic fibrosis.
Do I need to fast before this test?
Your doctor will provide specific instructions. Generally, you may be asked to avoid certain foods or supplements for a short period before collection. Follow all pre-test instructions carefully for accurate results.
Are there any risks with this test?
There are no direct risks to the patient. The test only requires a stool sample, which is non-invasive. The main consideration is proper sample collection and handling.
How long does it take to get results?
Results typically take 1-3 days, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy