Complete Blood Count (CBC): What You Need to Know About This Common Blood Test
A urine test that measures the amount of chloride in your urine to evaluate your body's electrolyte balance and kidney function.
{"Measures chloride levels in urine to assess electrolyte balance","Helps diagnose kidney disorders, dehydration, and acid-base imbalances","Results are often interpreted alongside other electrolyte tests","Normal urine chloride varies with diet and fluid intake","Abnormal results may indicate adrenal or kidney problems"}
Key facts at a glance
- LOINC
- 2078-4
- Short code
- CLU
- Synonyms
- Chloride Ur-sCnc
- Category
- electrolyte
- Sample
- urine
- Container
- Sterile plastic urine container (without preservative for routine analysis)
- Units
- not specified
- Ref low
- 20
- Ref high
- 40
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Ion-selective electrode (ISE) potentiometry or chlorimetric method
- CPT
- 82436
- SNOMED
- 271344005
- Specimen volume
- 10-50 mL minimum; 24-hour collection requires total volume
- Stability
- Room temperature: 24-48 hours; Refrigerated (2-8°C): 5-7 days; Frozen (-20°C): 30 days
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 1–24 hours
- Order
- routine
The Complete Blood Count, often abbreviated as CBC, is a standard blood test that provides valuable information about the cells in your blood, including red blood cells, white blood cells, and platelets. It helps doctors evaluate your overall health and detect a wide range of disorders, such as anemia, infection, and even some cancers. In simple terms, it measures the different components of your blood to give a snapshot of your current health status.
The urine chloride test measures the concentration of chloride, an important electrolyte, in your urine. Chloride is a mineral that works with other electrolytes like sodium and potassium to maintain proper fluid balance, nerve function, and acid-base equilibrium in your body. This test is typically part of a comprehensive metabolic panel or electrolyte panel to evaluate how well your kidneys are regulating electrolyte levels.
Your healthcare provider may order a CBC as part of a routine physical exam, to check for conditions like anemia or infection, or to monitor the effects of certain medications that can affect blood cell counts. It is also commonly used to help diagnose symptoms such as fatigue, weakness, fever, bruising, or unusual bleeding. Additionally, it can be used to track the progress of treatment for diseases like leukemia or to evaluate the impact of chemotherapy, making it a versatile tool in both preventive and diagnostic medicine.
Your healthcare provider may order a urine chloride test to: evaluate kidney function and the kidneys' ability to regulate electrolytes, assess hydration status, diagnose causes of abnormal blood pressure, identify acid-base balance disorders (such as metabolic alkalosis), monitor certain conditions like Addison's disease or kidney disease, and check the effectiveness of diuretic therapy or salt-restricted diets.
The CBC test is performed by drawing a small sample of blood, usually from a vein in your arm. A healthcare professional will clean the area, apply a tourniquet to make the vein more visible, and insert a thin needle to collect the blood into a vial. The process typically takes only a few minutes and is relatively painless, with most people experiencing just a quick pinch. After the blood is drawn, the needle is removed, and you may be asked to apply pressure to the site to stop any bleeding. The sample is then sent to a laboratory for analysis, and results are usually available within a day or two.
The test requires a urine sample, typically collected as a 'clean catch' midstream urine sample. You will be given a sterile container and instructions to clean the genital area before collecting the sample. For a 24-hour urine collection, you will collect all urine produced over a 24-hour period in a special container. The sample is then sent to a laboratory where the chloride concentration is measured using specialized equipment.
Your CBC results are typically reported as a series of numbers and ranges that reflect your blood cell counts. The key components include red blood cell count, hemoglobin, hematocrit, white blood cell count, and platelet count. Your doctor will interpret these values in the context of your age, sex, medical history, and any symptoms you may have. Abnormal levels can indicate various conditions, but they are not a diagnosis on their own. For example, a low hemoglobin might suggest anemia, while a high white blood cell count could point to infection or inflammation. Your healthcare provider will explain what your results mean and discuss any further tests or treatments if needed.
Normal urine chloride levels vary widely depending on diet, fluid intake, and time of day. Generally, normal values range from 20-250 mEq/L in a random sample, but reference ranges may differ between laboratories. Your doctor will interpret your results in context with other test results, your symptoms, and your overall health status. A single abnormal result does not necessarily indicate a problem—multiple tests over time provide better assessment.
Reference range
20-40 mmol/Lnot specified
No special preparation required
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated urine chloride (chloruresis) may indicate: excessive salt intake, diuretic use, Addison's disease (adrenal insufficiency), kidney disease affecting electrolyte regulation, metabolic alkalosis, or certain medications. Low urine chloride may suggest: dehydration, inadequate salt intake, congestive heart failure, syndrome of inappropriate antidiuretic hormone secretion (SIADH), or certain kidney disorders that cause excessive salt retention. The urine chloride test is particularly useful when interpreted alongside blood chloride, sodium, potassium, and bicarbonate levels to get a complete picture of electrolyte and acid-base status.
Frequently asked questions
Do I need to fast before this test?
Can I take my medications before the test?
What happens if my results are abnormal?
How is this test different from blood chloride testing?
Does diet affect urine chloride levels?
Sources
- 1
- 2Mayo Clinic - UrinalysisSource
- 3
- 4
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy