Complete Blood Count (CBC): What You Need to Know
A laboratory test that measures chloride levels in the vitreous fluid of the eye.
{"Measures chloride concentration in the vitreous humor of the eye","Helps evaluate electrolyte balance and eye health","Used primarily in ophthalmology and forensic medicine","Abnormal levels may indicate underlying systemic or ocular conditions","Sample is collected from the vitreous cavity of the eye"}
Key facts at a glance
- LOINC
- 12898-3
- Short code
- Cl-Vitreous
- Synonyms
- Chloride Vitf-sCnc
- Category
- electrolyte
- Sample
- serum
- Container
- Sterile glass or plastic container, typically collected via vitreous tap (vitreocentesis) using a 19-22 gauge needle
- Units
- not specified
- Ref low
- 105
- Ref high
- 135
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Ion-selective electrode (ISE) potentiometry or indirect potentiometry
- CPT
- 82436 ( Chloride, body fluid ) or 84305 ( Electrolyte panel, body fluid )
- SNOMED
- 39654006 ( Chloride measurement ) or 27922009 ( Vitreous fluid )
- Specimen volume
- 0.5-2.0 mL preferably, minimum 0.2 mL for analysis
- Stability
- Stable for 24-48 hours at 2-8°C; avoid freezing as this may cause cell lysis; analyze as soon as possible
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
This test measures the different types of cells in your blood, including red blood cells, white blood cells, and platelets. It helps evaluate your overall health and detect a variety of disorders, such as anemia, infection, and certain blood cancers.
The Vitreous Fluid Chloride test measures the concentration of chloride, an important electrolyte, in the vitreous humor—the clear, gel-like substance that fills the space between the lens and the retina of the eye. Chloride is a negatively charged ion that helps maintain the body's fluid balance, acid-base balance, and is essential for proper nerve and muscle function.
A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. You may feel a quick sting, but the process is generally safe and takes only a few minutes.
A small sample of vitreous fluid is collected from the eye using a thin needle in a procedure called vitreous aspiration or vitrectomy. This procedure is typically performed by an ophthalmologist in a clinical setting. The collected sample is then sent to a laboratory where the chloride concentration is measured using specialized equipment.
The CBC is important because it provides critical information about your blood health. Abnormal results can help diagnose conditions like anemia, infections, bleeding disorders, or even more serious issues such as leukemia. Regular testing can also help monitor the effects of treatments or medications on your blood cells.
Chloride plays a crucial role in maintaining the electrical neutrality and osmotic balance of the eye's internal environment. Abnormal chloride levels in the vitreous fluid can indicate various conditions affecting the eye or systemic electrolyte imbalances. This test provides valuable diagnostic information that cannot be obtained from blood tests alone.
Reference range
105-135 mmol/Lnot specified
Postmortem specimen; no living patient preparation required
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The vitreous fluid chloride test is primarily used in ophthalmology to assess intraocular electrolyte status. Elevated or decreased chloride levels may indicate conditions such as uveitis (inflammation of the eye), retinal detachment, or other ocular diseases. In forensic medicine, analysis of vitreous humor electrolytes can help determine the cause and time of death, as postmortem changes in the eye occur more slowly than in other body fluids.
Abnormal chloride levels may also reflect systemic electrolyte disturbances, dehydration, kidney disorders, or certain metabolic conditions. The test helps ophthalmologists and other healthcare providers make accurate diagnoses and develop appropriate treatment plans for eye-related conditions.
Frequently asked questions
Is the vitreous fluid chloride test painful?
How long does it take to get results?
Are there any risks associated with this test?
Do I need to fast before the test?
How should I prepare for the test?
Sources
- 1LOINC Code ReferenceSource
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy