Cholesterol (Total) with High-Density Lipoprotein (HDL) Subfraction Analysis by Electrophoresis

Why This Test Matters for Heart Health

Cholesterol is a critical fat in your body, but too much can build up in your arteries, increasing the risk of heart disease. HDL is often called 'good cholesterol' because it helps remove excess cholesterol from arteries. This test helps doctors understand your overall cholesterol picture and whether HDL is functioning properly.

How the Test Works

Blood is drawn and processed to separate components. Electrophoresis then separates HDL into different subfractions (e.g., HDL1, HDL2) based on their movement in an electric field, allowing for a detailed analysis of cholesterol distribution.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 12 hours before the test if cholesterol levels are being evaluated for clinical reasons. Wear comfortable clothing and plan for the blood draw.

Common Results and Interpretation

Results provide total cholesterol and HDL subfraction details. While specific reference ranges vary by lab, doctors use these results alongside other factors (like diet, family history, and symptoms) to assess cardiovascular risk.