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Total Cholesterol (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which includes both the cholesterol your body makes and the cholesterol you get from foods.

Quick summary

["Cholesterol levels help assess your heart health risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57935-9
Short code
Chocolate IgE/IgE total %
Synonyms
Chocolate IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for high cholesterol, which can increase your risk of heart disease, stroke, or other health problems. It’s often done as part of a routine check-up or if you have risk factors like high blood pressure, a family history of heart disease, or obesity.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 9–12 hours before the test if your blood is drawn early in the morning. If you’re unsure, ask your provider. The test is usually done by having a small needle inserted into your arm to draw blood.

What the Results Mean

While specific ranges vary by lab, high cholesterol levels (above typical reference ranges) may signal a need for lifestyle changes or medication to lower it. Low levels might raise concerns about nutrient absorption or other health conditions, so results should always be discussed with your provider.

Common Causes of Abnormal Results

High cholesterol can result from diet, genetics, or conditions like diabetes or obesity. Low cholesterol may occur due to liver disease, malnutrition, or certain medications. Your provider will consider your full medical history when interpreting results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Cholesterol

Frequently asked questions

How often should I get this test?
Typically, adults are advised to have cholesterol tests every 4–5 years if they have no risk factors. If you have risk factors (like high blood pressure or a family history of heart disease), your provider may recommend more frequent testing, possibly every 1–2 years.
What should I do if my cholesterol is high?
If your cholesterol is high, your provider may suggest lifestyle changes such as eating a heart-healthy diet (low in saturated fats), exercising regularly, and avoiding smoking. If needed, they may also prescribe medications like statins to help lower cholesterol levels.
Does diet affect cholesterol test results?
Yes, diet can impact cholesterol levels. Fatty foods (like fried foods or red meat) can raise cholesterol, while fruits, vegetables, and whole grains can help lower it. If fasting is required, avoid high-fat foods before your blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy