Skip to content

Cholesterol Esters, Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures cholesterol esters in blood to help assess cholesterol metabolism and the risk of cardiovascular disease.

Quick summary

["This blood test measures the portion of cholesterol that is bound to fatty acids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55840-3
Short code
Cholest Ester SerPl-sCnc
Synonyms
Cholest Ester SerPl-sCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Cholesterol esters are formed when cholesterol is attached to a fatty acid. This test measures their concentration in serum or plasma and provides information about the amount of cholesterol circulating in the blood.

Why might I need this test?

This test may be ordered as part of a lipid panel or when evaluating high cholesterol, cardiovascular risk, or a possible inherited or secondary lipid disorder. It may also help monitor treatment intended to lower cholesterol.

How is the test performed?

A blood sample is collected, and the laboratory separates serum or plasma from the blood cells. The amount of cholesterol esters in the sample is then measured and reported as a substance concentration.

How do I prepare for the test?

Follow the instructions provided by your healthcare professional or laboratory. Fasting for 9 to 12 hours may be requested for lipid testing, and water is usually allowed. Do not stop prescribed medicines unless your clinician specifically tells you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cholesterol Esters

Frequently asked questions

Is a cholesterol ester test the same as a total cholesterol test?
No. Total cholesterol measures all cholesterol in the blood, while this test measures cholesterol that is chemically bound to fatty acids. One result may help explain the other.
Do I need to fast before this test?
Fasting may be required, especially when the test is part of a complete lipid panel. Ask your healthcare professional or laboratory for specific preparation instructions before the blood draw.
What can cause an abnormal result?
Diet, weight, diabetes, thyroid disorders, some medicines, and inherited conditions can affect cholesterol ester levels. Your clinician can interpret the result in light of your medical history and other lipid measurements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy