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Cholesteryl Ester Transfer Protein, Serum/Plasma — Analyte Concentration

Published: August 9, 2026Updated: August 16, 2026

A specialized blood test that measures cholesteryl ester transfer protein (CETP), a protein involved in moving cholesterol between different types of lipoproteins.

Quick summary

["This test measures a protein that helps regulate cholesterol transport in the blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55839-5
Short code
Cholest est trnsfr prot SerPl-aCnc
Synonyms
Cholest est trnsfr prot SerPl-aCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86592
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures cholesteryl ester transfer protein (CETP), which transfers cholesterol and other lipids among lipoproteins. CETP is produced mainly by the liver and plays a role in how the body handles cholesterol.

Why might I need this test?

This specialized test may be ordered by a clinician when evaluating unusual cholesterol levels, lipid metabolism, or a possible inherited lipid disorder. It is not usually part of a routine cholesterol screening panel.

How is the test performed?

A sample of blood is collected, usually from a vein, and sent to a laboratory. The laboratory measures CETP in the serum or plasma portion of the sample using a validated laboratory method.

How do I prepare for the test?

Follow the instructions provided by your clinician. If you are also having a standard lipid panel, you may be asked to fast for several hours, but fasting requirements for CETP measurement can vary and should be confirmed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CETP levels may be altered in inherited conditions affecting cholesterol transport and in some acquired conditions, including metabolic and liver disorders. A result should be interpreted with other lipid tests, medications, family history, and clinical findings because CETP levels alone do not establish a diagnosis.

Short name

CETP level

Frequently asked questions

Is this the same as a standard cholesterol test?
No. A standard lipid panel measures cholesterol and triglycerides, while this test measures the activity or amount of the CETP protein that helps transport cholesterol.
Why is CETP important?
CETP helps exchange cholesterol and triglycerides between high-density and other lipoproteins. Its amount or activity can influence how the body transports and regulates blood lipids.
Does an abnormal result mean I have heart disease?
No. An abnormal CETP result does not by itself diagnose heart disease. Your clinician will interpret it alongside your overall cholesterol profile, medical history, family history, and other risk factors.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy