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Cholesterol — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of cholesterol in a laboratory sample. Blood cholesterol is commonly used with other tests to help assess cardiovascular risk.

Quick summary

["This test measures cholesterol, which helps provide information about lipid status and cardiovascular risk when performed on a blood sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56912-9
Short code
Cholest Pcar-mCnc
Synonyms
Cholest Pcar-mCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This laboratory test measures the concentration of cholesterol in the submitted sample. When the sample is blood, the result may be used as part of an overall assessment of cholesterol levels and heart disease risk.

Why might I need this test?

Clinicians may order a cholesterol test to evaluate lipid status, monitor treatment or dietary changes, or help assess the risk of cardiovascular disease. Cholesterol may also be measured in other body-fluid samples in certain clinical situations.

How is the test performed?

A sample is collected and analyzed in the laboratory using a validated method that measures the amount of cholesterol present. If this is a blood test, the laboratory may use an enzymatic or colorimetric assay.

How do I prepare for the test?

Preparation depends on the type of sample and the instructions provided by your clinician. Some cholesterol tests require fasting; if fasting is requested, follow the clinic's instructions and avoid food and drinks other than water for the specified period.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Higher cholesterol levels can increase the risk of plaque buildup and cardiovascular disease, particularly when accompanied by high triglycerides, low HDL cholesterol, or other risk factors. Lower-than-expected values may occur with certain illnesses, poor nutrition, or other clinical conditions. Interpretation depends on the sample type, the method used, and the reference range appropriate for that test.

Short name

Cholesterol

Frequently asked questions

Does a cholesterol test require fasting?
Some tests do and some do not. Follow the specific instructions from your clinician or laboratory, because fasting requirements and allowable fasting times can vary.
Is cholesterol the same as HDL or LDL?
No. Total cholesterol includes several forms of cholesterol carried in the blood, including HDL and LDL. A lipid panel usually reports these components separately.
Can this test be performed on samples other than blood?
Yes. Cholesterol can be measured in certain other body fluids when clinically appropriate. The specimen and reference range should be confirmed on the laboratory report.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy