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Cholesterol, Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the concentration of cholesterol in a blood sample. The result may be used to assess cardiovascular risk and other conditions.

Quick summary

["This test measures blood cholesterol to help assess cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78518-8
Short code
Cholest Pcar-sCnc
Synonyms
Cholest Pcar-sCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A cholesterol concentration test measures the amount of cholesterol in a blood sample. It may be used alone or as part of a broader lipid panel.

Why might I need this test?

Your clinician may order this test to evaluate cardiovascular risk, monitor cholesterol-lowering treatment, or investigate symptoms or conditions that may affect cholesterol levels.

How is the test performed?

A blood sample is collected and analyzed in a laboratory using a validated chemical or enzymatic method. The exact specimen and reported units depend on the laboratory test ordered.

How do I prepare for the test?

Follow your clinician's fasting instructions. Some cholesterol tests are done without fasting, while others may require you to avoid food for several hours. Drinking water is usually allowed unless you are told otherwise.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated cholesterol concentrations can increase the risk of plaque buildup and cardiovascular disease. Low cholesterol may occur with certain illnesses, inadequate nutrition, or some medications. Results should be interpreted with other risk factors and the rest of your lipid panel.

Short name

Cholesterol test

Frequently asked questions

Does this test require fasting?
It depends on the test and the instructions from your clinician. Fasting may be requested, but many cholesterol measurements can be performed without fasting.
Is a high cholesterol result an emergency?
A mildly elevated result is usually addressed through follow-up and risk assessment rather than emergency care. Seek urgent care for chest pain, severe shortness of breath, or other acute symptoms.
What can affect my cholesterol result?
Diet, weight, physical activity, illness, pregnancy, and medications can influence cholesterol levels. A recent change in these factors may affect the result.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy