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Cholesterol, Serum/Plasma — Concentration

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures cholesterol in serum or plasma to help assess cardiovascular risk and monitor cholesterol-lowering treatment.

Quick summary

["This test helps determine whether your cholesterol level may increase your risk of heart disease or stroke."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51591-6
Short code
Cholest Snv-sCnc
Synonyms
Cholest Snv-sCnc
Category
lipid
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the concentration of cholesterol in serum or plasma. It may be used alone or as part of a lipid panel that also measures triglycerides and other types of cholesterol.

Why might I need this test?

Your doctor may order this test to assess your risk of heart disease and stroke, especially if you have high blood pressure, diabetes, a family history of cardiovascular disease, or other risk factors. It is also commonly used to monitor diet, weight changes, and cholesterol-lowering medicines.

How is the test performed?

A healthcare professional draws a blood sample from a vein. The laboratory separates the serum or plasma and analyzes it to determine the cholesterol concentration.

How do I prepare for the test?

Follow your doctor's instructions about fasting. Some cholesterol tests do not require fasting, while others may ask you to fast for about 8 to 12 hours. You may usually drink water, and medicines and supplements should be taken unless your healthcare professional tells you otherwise.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cholesterol test

Frequently asked questions

Does this test measure all types of cholesterol?
Not necessarily. A total cholesterol test measures cholesterol overall, while a lipid panel also measures HDL, LDL, and triglycerides.
Do I need to fast before a cholesterol test?
It depends on the test and your doctor's instructions. Many cholesterol tests can be done without fasting, although fasting may be requested for more standardized results.
How often is cholesterol checked?
The interval depends on your age, health risks, previous results, and any treatment you are receiving. Your doctor can recommend a schedule appropriate for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy