Chromosomal Fluorescence In Situ Hybridization (FISH) Analysis for Aneuploidy on Chromosome 13
This test checks for extra or missing copies of chromosome 13 in your cells, which may be linked to genetic conditions or cancer risk.
["Assesses genetic balance on chromosome 13 to identify potential chromosomal abnormalities."]
Key facts at a glance
- LOINC
- 57454-1
- Short code
- Chr 13 aneup Amn/CVS FISH
- Synonyms
- Chr 13 aneup Amn/CVS FISH
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- fish
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or risk factors for genetic disorders, such as Patau syndrome (a rare chromosomal condition), or if you’re undergoing evaluation for certain cancers like bladder, breast, or ovarian cancer. It may also be used during pregnancy to screen for chromosomal abnormalities in the fetus.
How the Test Works
A small blood sample is taken to examine cells under a microscope. Fluorescent probes attach to specific parts of chromosome 13, allowing doctors to detect any extra or missing chromosomes with high precision.
Sample Collection and Preparation
Blood is drawn from a vein in your arm. The sample is processed to isolate cells, which are then prepared for microscopic analysis. This process usually takes a few days to complete.
What to Expect Before the Test
No special preparation is needed, but inform your doctor about any medications or supplements you’re taking, as some may affect test results. Avoid alcohol before the blood draw if instructed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal findings on this test may indicate conditions like trisomy 13 (Patau syndrome), which can cause developmental delays, heart defects, or other birth defects. In cancer screening, it helps assess genetic predispositions or tumor behavior. Results guide further diagnostic testing or treatment planning.
Short name
Chromosome 13 Aneuploidy Screening by FISH
Frequently asked questions
What does a positive result mean?
How long will I wait for results?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy