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Chromosome Analysis by Microarray (CMA)

Published: August 9, 2026Updated: August 16, 2026

This test examines your blood cells for genetic changes that may affect your health, often used to diagnose conditions like cancer, genetic disorders, or other genetic abnormalities.

Quick summary

["CMA helps identify hidden genetic issues that might not show up on standard blood tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94087-4
Short code
Chrom analy Bld/T Microarray
Synonyms
Chrom analy Bld/T Microarray
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microarray
CPT
86038
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

CMA detects differences in your chromosomes, which are the structures that carry your genes. It looks for extra, missing, or rearranged pieces of DNA that could influence how your body functions or lead to disease.

How the Test Works

A small sample of your blood is taken and processed to isolate your white blood cells. These cells are then analyzed using a specialized microarray technique that compares your genetic material to a reference database.

Why It’s Done

Doctors may recommend CMA if you have symptoms of a genetic disorder, a family history of genetic conditions, or if other tests (like standard karyotyping) show unclear results. It’s also used in prenatal testing or to guide treatment decisions for certain cancers.

Common Uses

CMA is commonly used for diagnosing conditions such as Down syndrome, cancer (like lymphoma or leukemia), or genetic syndromes. It can also help determine the cause of unexplained developmental delays or birth defects.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CMA

Frequently asked questions

How long will it take to get my results?
Results from CMA are typically available within 1–2 weeks, depending on the lab and complexity of your test. Your healthcare provider will discuss the findings with you.
What does a positive result mean?
A positive result means genetic changes were found that may explain your symptoms or health concerns. These changes could indicate a genetic disorder, cancer, or other conditions. Your doctor will explain the implications and next steps based on your specific findings.
Can I fast before this test?
No fasting is required for CMA. You may eat and drink normally before the blood draw, as this test only involves collecting a small sample of your blood.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy