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Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of fat-protein particle that carries cholesterol. It may help assess your risk for heart disease.

Quick summary

["Lipoprotein(a) levels can provide insight into cardiovascular risk beyond standard cholesterol measures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62346-2
Short code
Chrom analy interphase pnl Amn FISH
Synonyms
Chrom analy interphase pnl Amn FISH
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
fish
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares some traits with cholesterol, it behaves differently in the body. High levels may increase your risk of clots and heart disease.

Why Might You Need This Test?

Your doctor may order this test if you have a family history of heart disease, stroke, or blood clots, or if you have conditions like high cholesterol or peripheral artery disease. It can also be used to monitor treatment for certain genetic conditions.

How Is the Test Done?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab for analysis using a specialized method to measure lipoprotein(a) levels precisely.

What Does the Test Result Mean?

Results are typically reported as a numerical value indicating the concentration of lipoprotein(a) in your blood. While there are no universally accepted reference ranges for everyone, high levels may signal increased cardiovascular risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lipoprotein(a) is considered an independent risk factor for cardiovascular disease, including atherosclerosis and arterial thrombosis. It may contribute to plaque buildup in arteries and increase the risk of heart attacks or strokes, particularly in people with genetic predispositions or other risk factors like smoking, diabetes, or high blood pressure.

Short name

Lp(a) Level

Frequently asked questions

What causes variations in lipoprotein(a) levels?
Lipoprotein(a) levels are largely determined by genetics and cannot be changed through diet or lifestyle alone. However, managing other cardiovascular risk factors—such as blood pressure, cholesterol, and smoking—may indirectly influence overall heart health.
Can lifestyle changes affect lipoprotein(a) levels?
No, lifestyle changes like diet or exercise typically do not significantly alter lipoprotein(a) levels. However, controlling other risk factors (e.g., hypertension, diabetes) remains important for overall cardiovascular health.
Is this test covered by insurance?
Coverage depends on your insurance plan and clinical indication. If ordered for a specific condition (e.g., genetic screening, cardiovascular risk assessment), check with your provider or insurance company for details.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy