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Chromatin Interphase Protein Analysis (Fish Method) - Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures specific proteins found in blood cells during the resting phase of cell division (interphase). It may be used to assess cellular health or detect abnormalities in certain blood conditions.

Quick summary

["This test helps evaluate how chromatin proteins behave in your blood cells, potentially aiding in diagnosing or monitoring blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62345-4
Short code
Chrom analy interphase pnl Bld FISH
Synonyms
Chrom analy interphase pnl Bld FISH
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
fish
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, unusual bleeding, or if they suspect conditions affecting blood cell function, such as certain cancers, immune disorders, or genetic syndromes. It could also be part of a broader evaluation for unexplained anemia or white blood cell abnormalities.

What to Expect Before the Test

No special preparation is typically needed. You may fast before the test if instructed, but this is not always required. Bring any medications or supplements you’re currently taking, as they may affect results.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it usually doesn’t cause significant discomfort. The blood sample is then processed to analyze chromatin interphase proteins using a specialized fish-based assay method.

What the Results Mean

Results are qualitative (yes/no or present/absent) and may indicate whether abnormal levels of chromatin proteins are present. Your provider will interpret these results in the context of your medical history and symptoms to guide diagnosis or treatment planning.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fish Assay for Chromatin Interphase Proteins

Frequently asked questions

What does this test measure?
This test measures the presence of specific proteins associated with chromatin during the interphase of blood cells. Abnormal findings may suggest underlying genetic, metabolic, or hematologic conditions that require further evaluation.
How might my results affect my treatment?
If your results show abnormal chromatin protein levels, your healthcare provider may recommend additional testing, such as genetic analysis, blood cell counts, or other specialized evaluations to determine the cause and guide treatment options.
Can this test detect early signs of disease?
While this test may help identify certain blood-related abnormalities, it is not a general screening tool for early disease detection. It is typically used in specific clinical scenarios, often alongside other diagnostic tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy