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Chromatographic Analysis of Protein Electrophoresis Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood, often used to identify conditions affecting protein balance.

Quick summary

["Helps diagnose and monitor protein disorders, including kidney disease or liver issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64090-4
Short code
Chrom analy overall interp Spec-Imp
Synonyms
Chrom analy overall interp Spec-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Being Tested?

Electrophoresis separates blood proteins by size and charge, revealing patterns of albumin, globulins, and other proteins. Abnormal separations may suggest conditions like multiple myeloma, liver disease, or kidney problems.

How Is This Test Performed?

A blood sample is drawn, and proteins are separated using an electric current in a gel. Results are interpreted to compare protein levels across different fractions.

Common Conditions Monitored

This test is used to detect imbalances in protein fractions, such as low albumin (common in kidney disease) or abnormal globulin patterns (linked to immune disorders).

How Long Until Results Are Ready?

Results are typically available within 24 to 48 hours, depending on lab processing times.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis Profile

Frequently asked questions

Why did my doctor order this test?
Your doctor may recommend this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if they suspect a protein-related disorder (e.g., kidney, liver, or blood disease).
What does a ‘qualitative’ or ‘screening’ result mean?
A screening result shows whether protein patterns appear abnormal but does not provide exact measurements. Confirmatory testing may be needed for a full diagnosis.
Can I eat or drink before this test?
For most protein electrophoresis tests, fasting is not required, but follow your doctor’s specific instructions regarding food or medications to avoid interference.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy