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Chromatography-based protein electrophoresis of serum/plasma (qualitative or semi-quantitative analysis of protein bands)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood using gel electrophoresis, helping identify patterns that may indicate conditions like kidney disease, liver problems, or other disorders affecting protein production.

Quick summary

["Electrophoresis helps diagnose protein abnormalities by separating blood proteins for closer inspection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62350-4
Short code
Chrom analy pnl CVS G-banded
Synonyms
Chrom analy pnl CVS G-banded
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
g-banded
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on their size and electrical charge. Different protein groups (such as albumin, globulins, and other fractions) move at distinct speeds, creating visible bands on a gel. These bands can reflect normal protein levels or signs of disease.

How the Test Works

A small blood sample is drawn and mixed with a buffer solution. An electric current is applied, causing proteins to migrate through a gel matrix. After separation, the gel is stained to reveal distinct protein bands, which are then analyzed for patterns or abnormalities.

Common Uses

This test is often used to diagnose conditions like multiple myeloma, nephrotic syndrome, liver disease, or certain autoimmune disorders. It may also help monitor treatment progress or identify hidden protein imbalances.

When You Might Need This Test

Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect a condition affecting protein production or kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis (Serum/Plasma)

Frequently asked questions

Why might my doctor order this test?
Your doctor may use the results to confirm or rule out diseases like kidney disease, liver disease, or certain cancers. Abnormal band patterns can indicate low albumin, high globulin levels, or unusual protein fragments that may signal underlying health issues.
What do the results mean?
Results show the distribution of protein bands. Normal results have distinct bands with expected spacing. Abnormal results may show missing bands, extra bands, or shifts in protein distribution, which could point to specific health concerns.
How long will it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your doctor is needed to discuss findings and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy