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Chymopapain (Serum/plasma Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of chymopapain, an enzyme used in medical treatments for conditions like osteoarthritis or chronic pain. It may be ordered to monitor its effectiveness or assess how your body processes it.

Quick summary

["Chymopapain helps relieve joint pain and improve mobility in certain conditions; your levels may be checked during treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102238-3
Short code
Chymopapain IgE RAST
Synonyms
Chymopapain IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Chymopapain Used For?

Chymopapain is an enzyme derived from papaya that breaks down proteins in the body. In medical use, it’s injected to reduce inflammation and pain in joints affected by conditions like osteoarthritis or rheumatoid arthritis. It may also be used in other treatments where protein breakdown is beneficial.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then separated into serum or plasma for testing. The enzyme activity is measured using specialized laboratory techniques, often involving enzymatic assays to detect and quantify chymopapain.

Why Might This Test Be Ordered?

Your healthcare provider may order this test if you’re receiving chymopapain therapy to monitor its effectiveness, check for side effects, or assess how well your body is processing the medication. It could also be part of a broader evaluation for conditions where enzyme activity is relevant.

What Do Results Mean?

Results are typically reported as a mass concentration (e.g., in micrograms per milliliter or another unit). While reference ranges vary by lab, abnormal levels may indicate issues with enzyme function, treatment response, or potential side effects. Your provider will interpret results in the context of your medical history and symptoms.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chymopapain Level

Frequently asked questions

Why do I need this test?
Your doctor may recommend this test if you’re receiving chymopapain injections for pain relief or joint treatment. It helps track how well the medication is working and ensures there are no unexpected changes in your body’s response.
What are the normal results?
There are no universally standardized reference ranges for chymopapain because it’s not a standard lab test. Your results will be compared to your baseline and clinical picture, not a fixed range.
Can I prepare for this test?
No special preparation is needed. Avoid alcohol for 24 hours before the test if advised, as it may affect blood test results. Bring any medications or questions to your appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy