Chymopapain (Serum/plasma Mass Concentration)
This test measures the amount of chymopapain, an enzyme used in medical treatments for conditions like osteoarthritis or chronic pain. It may be ordered to monitor its effectiveness or assess how your body processes it.
["Chymopapain helps relieve joint pain and improve mobility in certain conditions; your levels may be checked during treatment."]
Key facts at a glance
- LOINC
- 102238-3
- Short code
- Chymopapain IgE RAST
- Synonyms
- Chymopapain IgE RAST
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- rast
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Chymopapain Used For?
Chymopapain is an enzyme derived from papaya that breaks down proteins in the body. In medical use, it’s injected to reduce inflammation and pain in joints affected by conditions like osteoarthritis or rheumatoid arthritis. It may also be used in other treatments where protein breakdown is beneficial.
How Is This Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then separated into serum or plasma for testing. The enzyme activity is measured using specialized laboratory techniques, often involving enzymatic assays to detect and quantify chymopapain.
Why Might This Test Be Ordered?
Your healthcare provider may order this test if you’re receiving chymopapain therapy to monitor its effectiveness, check for side effects, or assess how well your body is processing the medication. It could also be part of a broader evaluation for conditions where enzyme activity is relevant.
What Do Results Mean?
Results are typically reported as a mass concentration (e.g., in micrograms per milliliter or another unit). While reference ranges vary by lab, abnormal levels may indicate issues with enzyme function, treatment response, or potential side effects. Your provider will interpret results in the context of your medical history and symptoms.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Chymopapain Level
Frequently asked questions
Why do I need this test?
What are the normal results?
Can I prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy