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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16634-8
Short code
C immitis Ab CSF-aCnc
Synonyms
C immitis Ab CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

C-reactive protein (CRP) is a substance that your liver produces when there is inflammation somewhere in your body. A simple blood test measures the amount of CRP in your blood, helping your doctor detect and monitor conditions such as infections, autoimmune diseases, and inflammation linked to heart disease.

C-reactive protein (CRP) is a marker produced by your liver when your body detects inflammation. It rises in response to injuries, infections, or conditions causing chronic inflammation, such as arthritis or heart disease. This test helps doctors assess whether inflammation is present and guide treatment decisions.

Your doctor may order this test if you have symptoms of an infection or an inflammatory condition, such as fever, fatigue, unexplained pain, or swelling. It is also used to monitor chronic diseases like rheumatoid arthritis or lupus, check how well a treatment is working, and help evaluate your risk for cardiovascular problems.

Your doctor may order a CRP test to monitor conditions like infections, autoimmune diseases (e.g., rheumatoid arthritis), or to check for signs of inflammation before or after treatments. It can also help evaluate heart disease risk or assess response to treatments.

The test is a straightforward blood draw. A healthcare professional will clean the skin on your arm, wrap a band around your upper arm, and collect a small sample of blood from a vein, usually in the crook of your elbow. The procedure takes only a few minutes, causes little discomfort, and you can return to your normal activities right away.

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure CRP levels. No special preparation is usually needed, but fasting may be advised in some cases.

CRP results are reported in milligrams per liter (mg/L). Higher-than-normal levels indicate inflammation in your body, but the test does not reveal where the inflammation is located or what is causing it. Very high levels may suggest a serious infection, while mildly elevated levels can point to chronic inflammation or increased heart disease risk. Your doctor will interpret your results together with your symptoms and other tests.

Results are interpreted based on your overall health and medical history. Higher CRP levels may indicate inflammation, while lower levels suggest reduced inflammation. Your doctor will discuss findings with you in the context of your specific situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (Serum/Plasma)

Frequently asked questions

How often should I get this test?
For most healthy adults, CRP levels below 1.0 mg/L are considered low risk, levels between 1.0 and 3.0 mg/L indicate average risk, and levels above 3.0 mg/L suggest a higher risk of cardiovascular disease or active inflammation. Results above 10 mg/L often point to an acute infection or significant inflammation. Your doctor will explain what your specific values mean.
There are no strict 'normal' ranges for CRP because they vary by age, health, and condition. Low levels (often below 1 mg/L) suggest minimal inflammation, while higher levels may signal active inflammation or infection. Your doctor will compare your results to your specific health needs.
Yes, they can. Regular physical activity, maintaining a healthy weight, quitting smoking, and following a heart-healthy diet rich in fruits, vegetables, and whole grains may help lower CRP levels over time. Managing conditions such as diabetes, high blood pressure, and high cholesterol can also reduce chronic inflammation and improve your results.
Yes! Lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. Reducing inflammation through healthy eating, regular activity, and avoiding smoking may lower CRP levels over time. Always discuss changes with your doctor.
High CRP levels may prompt further testing or treatment adjustments. Your doctor could recommend additional tests (like blood cultures or imaging) to identify the cause of inflammation. Treatment might include medications, lifestyle changes, or monitoring for underlying conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy