Cerebrospinal Fluid Immunoglobulin (Ig) Profile (Screening)

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like headaches, neurological issues, or signs of an infection or inflammation in your central nervous system. It could also be used to monitor conditions like multiple sclerosis, Guillain-Barré syndrome, or other immune-related disorders affecting the brain or spinal cord.

What to Expect Before the Test

You’ll likely have a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect a sample of CSF. This is usually done in a hospital setting with sedation or local anesthesia. You may feel mild pressure afterward, but it’s generally not painful.

What the Test Results Mean

Results show the presence and levels of different immunoglobulins (IgG, IgA, IgM) in the CSF. Elevated levels of certain antibodies may indicate an immune response, infection, or inflammation. Your doctor will interpret the results in the context of your symptoms and medical history.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions such as multiple sclerosis, meningitis, encephalitis, or other neurological disorders linked to abnormal immune activity in the CSF.