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Serum or Plasma Immunoassay for Anti-Mycoplasma pneumoniae Antibodies (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that your immune system makes in response to *Mycoplasma pneumoniae*, a type of bacteria that can cause respiratory infections like pneumonia or bronchitis.

Quick summary

["Helps diagnose infections caused by *Mycoplasma pneumoniae* when symptoms like cough or fever appear."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22208-3
Short code
C immitis Ab Titr Ser
Synonyms
C immitis Ab Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms such as persistent cough, chest pain, or fever that don’t improve with standard antibiotics. It’s often used when other causes of respiratory illness are ruled out.

How the Test Works

A small blood sample is taken, and the lab uses an immunoassay (a sensitive test that detects specific antibodies) to identify whether your blood contains antibodies against *Mycoplasma pneumoniae*. The result is qualitative, meaning it only tells you if antibodies are present (positive) or not (negative).

What to Expect Before the Test

No special preparation is needed. You may have a slight bruise or soreness at the injection site, but this usually fades quickly. If you’re on blood-thinning medication, let your doctor know before the test.

What the Results Mean

A positive result means your immune system has likely been exposed to *Mycoplasma pneumoniae* in the past or is currently fighting an infection. A negative result suggests no recent exposure or infection. Results alone don’t confirm a diagnosis—your doctor will consider symptoms and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mycoplasma pneumoniae Antibody Test

Frequently asked questions

This test is particularly useful for diagnosing *Mycoplasma pneumoniae* infections in people who test negative for other common causes of respiratory illness (e.g., *Streptococcus pneumoniae*, *Chlamydophila pneumoniae*). It may also help monitor treatment response or rule out infection in complex cases.
What does a positive result mean? A positive result indicates your body has produced antibodies against *Mycoplasma pneumoniae*, which could mean you had an infection recently or were exposed. This doesn’t always mean you’re currently sick, but it supports a diagnosis if symptoms are present.
Can this test be used for everyone? This test is most helpful for adults and children with persistent respiratory symptoms. It’s not typically used for routine screening in asymptomatic individuals.
How soon will I get results? Results are usually available within 1–3 business days, depending on your lab’s processing time. Follow-up with your doctor to discuss next steps if needed.
Does this test replace other tests? No, this test is often used alongside other diagnostic tools (e.g., chest X-ray, culture tests) to confirm or rule out *Mycoplasma pneumoniae* infection.
What if I have allergies or sensitivities? If you have severe allergies, inform your healthcare provider before the blood draw to ensure proper precautions are taken.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy