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Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases by fighting off bacteria and viruses.

Quick summary

["IgG helps your immune system defend against infections and chronic illnesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13947-7
Short code
C immitis IgG Ser Ql IA
Synonyms
C immitis IgG Ser Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgG Serve in Your Body?

IgG is the most abundant antibody in your blood and plays a critical role in long-term immunity. It helps your body recognize and remember pathogens (like bacteria and viruses) to fight them more effectively in the future. IgG also crosses the placenta to provide passive immunity to your newborn.

Why Might Your Doctor Order This Test?

Your doctor may order an IgG test to check for low or high levels, which can indicate conditions like immune deficiencies, infections, autoimmune diseases, or certain types of cancer. It’s also used to monitor treatment responses in patients with chronic illnesses.

Common Reasons for Testing

Common reasons include diagnosing or monitoring conditions such as HIV/AIDS, chronic infections, autoimmune diseases (like lupus or rheumatoid arthritis), or immune system disorders. It may also be checked in newborns to assess maternal antibody transfer.

Sample Collection and Preparation

This test requires a blood sample drawn from a vein in your arm. You may feel a small pinch when the needle is inserted, but it usually doesn’t cause significant discomfort. The blood is collected in a special tube and sent to the lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Level

Frequently asked questions

What Are IgG Levels Used For?
IgG levels help determine if your immune system is functioning properly. Low IgG levels may suggest an immune deficiency or chronic illness, while very high levels could indicate chronic infections, certain cancers, or immune system overactivity. Your doctor will interpret results in the context of your overall health and symptoms.
How Often Should I Get This Test?
The frequency depends on your medical condition. If you have an ongoing health issue like an autoimmune disease or immunodeficiency, your doctor may recommend regular monitoring. Otherwise, this test is usually done only when needed for diagnosis or treatment planning.
What Happens If My IgG Levels Are Abnormal?
If your IgG levels are outside the expected range, your doctor may recommend further testing or adjustments to your treatment plan. This could include additional blood tests, lifestyle changes, or medications to support your immune system.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy