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: Citrate Synthase, Blood

Published: August 9, 2026Updated: August 16, 2026

: This test measures the activity or amount of citrate synthase, an enzyme important in cellular energy production, in a blood sample.

Quick summary

[": Citrate synthase testing is a specialized laboratory measurement, and results are interpreted by a healthcare provider in the context of your overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47841-2
Short code
Citrate Synthase Amnc-cCnt
Synonyms
Citrate Synthase Amnc-cCnt
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

: What Is Citrate Synthase?

: Citrate synthase is an enzyme found in the energy-producing structures of cells called mitochondria. It helps start a key series of chemical reactions that cells use to generate energy from nutrients. Because it is present in nearly all cells, it is sometimes measured as a marker of mitochondrial function or cellular energy metabolism.

: Why Might This Test Be Ordered?

: This is not a routine blood test. It may be used in specialized research or clinical settings to study mitochondrial function or certain metabolic conditions. Your healthcare provider would explain the specific reason if this test is being considered for you.

: How the Sample Is Collected

: The test is typically performed on a blood sample collected by a trained healthcare professional, usually from a vein in your arm. The sample is then processed and analyzed in a specialized laboratory. Follow any preparation instructions your provider gives you.

: What the Results Mean

: Results reflect the measured level or activity of citrate synthase in your sample. Because reference ranges and interpretation depend on the specific laboratory method used, your provider will review your result alongside your medical history and other tests. There is no single universal normal value.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Citrate synthase is a marker of mitochondrial and cellular energy metabolism. Abnormal or altered measurements may prompt further evaluation of metabolic or mitochondrial function, but results must always be interpreted by a qualified healthcare professional in the context of the individual patient.

Short name

: NONE

Frequently asked questions

: Is citrate synthase a standard blood test?
: No. It is a specialized measurement used mainly in research or selected clinical settings rather than routine health screening.
: Do I need to fast before this test?
: Preparation depends on the specific laboratory and the reason for testing. Follow the instructions given by your healthcare provider or the testing laboratory.
: Can I interpret my citrate synthase result on my own?
: No. Results depend on the laboratory method and must be interpreted by your healthcare provider alongside your medical history and other findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy