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: Citrate, Timed Specimen, Urine, Quantitative

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of citrate in a timed urine collection. Citrate is a natural substance that helps keep urine from becoming too acidic and can influence the risk of certain types of kidney stones.

Quick summary

[": A timed urine citrate measurement helps your care team assess kidney stone risk and how well your body is handling urine chemistry."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41022-5
Short code
Citrate ?Tm sub Ur Qn
Synonyms
Citrate ?Tm sub Ur Qn
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

: What Is Being Tested

: Citrate is a small molecule produced naturally in your body and filtered into the urine by the kidneys. In urine, citrate helps bind calcium and makes the urine less likely to form certain crystals. Measuring it in a timed urine collection shows how much citrate your kidneys are passing over a defined period.

: How the Test Is Done

: You will collect all your urine over a set period (often 24 hours) in a container provided by the laboratory. The collection is timed from start to finish, and the total volume is recorded. Your provider or the lab will give you specific instructions on when to begin and end the collection.

: What the Results Can Mean

: Low urine citrate can occur with certain diets, some medical conditions, or medicines, and it is associated with a higher chance of forming some types of kidney stones. Results are interpreted together with urine volume, diet, other urine tests, and your medical history. Normal and abnormal cutoffs vary by laboratory and method, so your report’s own reference values are the ones that apply.

: Preparing for the Test

: Follow any instructions from your care team about food, fluids, and medicines before and during the collection. Because citrate can be affected by diet and by how completely you collect the urine, tell the laboratory if any urine was missed during the collection period.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Urine citrate testing is most often used to evaluate people who form kidney stones, especially calcium-based stones. Persistently low citrate can increase the risk of stone formation, and identifying it can guide dietary changes or medication. Results should always be interpreted by a clinician alongside other stone-risk tests and the overall clinical picture.

Short name

: Urine Citrate (Timed)

Frequently asked questions

: Does this test require a full 24-hour urine collection?
: Often, yes, but the collection time is set by your ordering provider or laboratory. The slug indicates a timed specimen, so follow the exact start and stop instructions you are given to ensure accuracy.
: Can my diet affect urine citrate?
: Yes. Diet can influence citrate levels, and certain foods, fluids, and supplements may change results. Your care team will tell you whether any food or fluid restrictions apply before and during collection.
: Are low citrate results always caused by kidney stones?
: No. Low urine citrate is a risk factor associated with some kidney stones, but it can also be influenced by diet, medicines, and other health conditions. Your clinician will interpret the result with your full history and other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy