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Carcinoembryonic Antigen (CEA) in Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of carcinoembryonic antigen, a protein sometimes produced by certain cancers, including colorectal, breast, and lung cancers.

Quick summary

["CEA helps monitor cancer progression or response to treatment in patients with known cancer diagnoses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
48163-0
Short code
CK 19 Fld-mCnc
Synonyms
CK 19 Fld-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Carcinoembryonic Antigen (CEA)?

Carcinoembryonic antigen (CEA) is a protein that can be found in small amounts in the blood of healthy people. However, higher levels may indicate the presence of certain cancers, such as colorectal, breast, or lung cancer. It can also be elevated in conditions like chronic inflammation or smoking.

Why Might You Need This Test?

Your healthcare provider may order a CEA test to monitor cancer progression, check for recurrence after treatment, or assess symptoms like unexplained weight loss, fatigue, or abdominal pain. It can also help evaluate if cancer has spread to other parts of the body.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a lab for analysis using an immunoassay method to detect and measure CEA levels.

What Do Results Mean?

Results are not always definitive on their own. Elevated levels may suggest cancer, but other conditions can also cause them. Your doctor will interpret results in the context of your medical history, symptoms, and other tests.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance:

Short name

CEA Serum

Frequently asked questions

How often should I get this test?
CEA testing frequency depends on your medical condition. If you have cancer, your doctor may recommend regular monitoring to track changes in your levels. If you’re at higher risk (e.g., due to family history or lifestyle factors), they may suggest periodic screening.
What are typical reference ranges?
Reference ranges vary by lab and individual health status. Generally, normal levels are below 5 ng/mL, but higher values may indicate concern. Your doctor will discuss your specific results with you.
Can lifestyle changes affect CEA levels?
Yes, factors like smoking, diet, and chronic inflammation can influence CEA levels. Avoiding smoking, managing weight, and reducing inflammation may help keep levels more stable.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy