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Carcinoembryonic Antigen (CEA) measured by Immunoassay (plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of carcinoembryonic antigen (CEA), a protein that may be produced by certain types of cancer, including colorectal, pancreatic, and breast cancer. It helps monitor cancer progression or recurrence.

Quick summary

["CEA levels can help track cancer treatment effectiveness and detect possible cancer spread."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
68929-9
Short code
CK 19 Pcar-mCnc
Synonyms
CK 19 Pcar-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Carcinoembryonic Antigen (CEA)?

Carcinoembryonic antigen (CEA) is a protein found in small amounts in the blood of healthy people. It is produced by certain types of cancer cells, particularly those from the colon, rectum, pancreas, and breast. In some cases, CEA levels can rise when cancer is present or when cancer has returned after treatment.

Why Might You Need This Test?

Your doctor may order a CEA test to monitor cancer treatment, check for cancer spread (metastasis), or evaluate symptoms like unexplained weight loss, fatigue, or abdominal pain. It’s often used alongside other tests to help diagnose or manage certain cancers.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab where it is analyzed using an immunoassay method to measure CEA levels. This process typically takes a few days to return results.

What Do the Results Mean?

CEA results are interpreted based on your medical history, symptoms, and other test results. Higher than normal levels may suggest cancer or other conditions affecting the liver or lungs. Your doctor will discuss the meaning of your specific results with you.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CEA is a tumor marker used primarily in the monitoring of colorectal, pancreatic, and breast cancers. While it can indicate cancer presence, it is not specific to any one type of cancer and may also be elevated in conditions like chronic liver disease, lung disease, or smoking. It is most useful when used alongside other diagnostic tests and clinical findings to guide treatment decisions.

Short name

CEA Plasma

Frequently asked questions

What causes CEA levels to change?
CEA levels can rise due to cancer growth, cancer spread (metastasis), or certain non-cancerous conditions like chronic liver disease, lung disease, or smoking. They may also fluctuate with treatment, such as chemotherapy or surgery.
How often should I get this test?
Your doctor will determine how often you need CEA testing based on your medical history, type of cancer, and treatment plan. Some patients may need regular monitoring, while others may only need it once or twice a year.
Can diet or lifestyle affect CEA levels?
Yes, certain foods, smoking, and chronic illnesses (like liver disease) may influence CEA levels. Your doctor may recommend lifestyle adjustments or fasting before the test to get the most accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy