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Serum Carcinoembryonic Antigen (CEA) Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of carcinoembryonic antigen (CEA), a protein sometimes produced by certain cancers, in your blood.

Quick summary

["CEA levels help monitor cancer progression or response to treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25390-6
Short code
CK 19 SerPl-mCnc
Synonyms
CK 19 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Carcinoembryonic Antigen (CEA)?

CEA is a protein found in small amounts in healthy people but can rise in certain cancers, such as colorectal, breast, or lung cancer. It’s also produced by some non-cancerous conditions, like chronic inflammation. Your doctor may order this test to check for cancer or track how well treatment is working.

Why Might You Need This Test?

Your healthcare provider may recommend a CEA test if you have a history of cancer, symptoms like unexplained weight loss, fatigue, or changes in bowel habits, or if you’re undergoing cancer treatment to monitor your condition.

How Is the Test Done?

A blood sample is taken from a vein in your arm. The blood is sent to a lab, where it’s analyzed to measure CEA levels using a specialized immunoassay method.

What Do Results Mean?

Results are compared to your baseline (previous levels) and general reference ranges. Higher than expected levels may signal cancer activity, while lower levels could indicate a positive response to treatment. Always discuss results with your doctor.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CEA Level

Frequently asked questions

What causes CEA levels to change?
CEA levels can be influenced by cancer progression, treatment responses, or non-cancerous conditions like chronic inflammation, infections, or smoking. If you have a history of cancer, your doctor may track CEA levels over time to assess changes.
How often should I get this test?
The frequency depends on your medical history and treatment plan. Your doctor will determine how often to check your CEA levels, often every few months during cancer treatment or surveillance.
Can diet or lifestyle affect CEA levels?
While diet and lifestyle factors like smoking or chronic inflammation can influence CEA levels, they don’t typically cause dramatic changes. Your doctor may recommend lifestyle adjustments if you have risk factors for cancer or other health concerns.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy