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Urine Thymidine Phosphorylase (TDP) Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of thymidine phosphorylase, an enzyme linked to certain cancers, in your urine. It may be used to help detect or monitor bladder, ovarian, or other cancers.

Quick summary

["This test helps doctors assess cancer risk or progression by analyzing urine enzyme levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
56787-5
Short code
CK 19 Ur-aCnc
Synonyms
CK 19 Ur-aCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82553
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent urinary changes, unexplained weight loss, or a history of cancer. It could also be part of routine surveillance for certain cancer types.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected in the morning. Avoid excessive fluid intake 2 hours before testing to ensure accurate results.

How the Test Works

Urine is analyzed using a specialized laboratory technique to measure thymidine phosphorylase levels. Elevated levels may suggest cancer activity, while normal results usually indicate no significant cancer presence.

Possible Results and Next Steps

Results are interpreted by your doctor based on your medical history. High levels may prompt further testing (e.g., biopsies or imaging), while low levels suggest no immediate concern but do not rule out cancer entirely.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: urine

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine TDP

Frequently asked questions

What Does a High Level Mean?
Elevated urine thymidine phosphorylase can signal cancer activity, particularly in bladder or ovarian cancers. It’s not definitive alone but often used alongside other tests for early detection or monitoring.
What If My Results Are Normal?
Normal results mean no detectable cancer activity in this sample, but they don’t guarantee you don’t have cancer. Follow-up tests or imaging may still be recommended based on your symptoms or risk factors.
How Often Should I Get This Test?
Your doctor will determine the frequency based on your diagnosis, symptoms, or cancer history. Regular monitoring may be needed if you have a history of cancer or specific risk factors.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy