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Serum or Plasma Creatinine Concentration (Electrophoresis-Based Qualitative Probe)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of creatinine in your blood, a waste product from muscle metabolism, using an electrophoresis-based method. It helps assess kidney function indirectly.

Quick summary

["This test helps check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72561-4
Short code
CK-AB CFr.DF SerPl Elph
Synonyms
CK-AB CFr.DF SerPl Elph
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Creatinine?

Creatinine is a small waste product made when your muscles break down proteins. Normally, your kidneys filter it out of your blood and remove it from your body through urine. High levels in your blood can indicate kidney problems.

Why Is This Test Done?

Your healthcare provider may order this test to monitor kidney function, especially if you have conditions like diabetes, high blood pressure, or a history of kidney disease. It can also be used to check for kidney damage before surgery or during treatment for certain illnesses.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then processed using electrophoresis, a technique that separates substances based on size and charge. The test identifies whether creatinine is present in your blood.

What Do the Results Mean?

Results are qualitative (yes/no) rather than quantitative, meaning they indicate whether creatinine is detected or not. If creatinine is detected, it suggests your kidneys may not be filtering blood as efficiently as they should.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

None

Frequently asked questions

How does this test help doctors?
This test helps detect early signs of kidney dysfunction by identifying elevated creatinine levels, which can indicate impaired kidney function. It’s particularly useful for monitoring chronic kidney disease, assessing pre-existing kidney conditions, or evaluating kidney function before certain procedures.
What if my creatinine test is positive?
A positive result (detected creatinine) means your kidneys may not be working as well as they should. Your doctor will likely order additional tests, such as urine tests or further blood tests, to determine the cause and guide treatment. Follow-up may include lifestyle changes, medications, or monitoring to manage kidney health.
Can I eat or drink before this test?
No special preparation is needed for this test. However, if you have a history of kidney issues or are on certain medications, always check with your healthcare provider before the test to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy