Myoglobin in Serum or Plasma by ElectrophoresisMedically reviewed by WellAlly Editorial Team·Last reviewed August 16, 2026·[Editorial policy](https://wellally.tech/editorial-policy)
## Key facts at a glance
LOINC12187-1Short codeCK MB CFr SerPl ElphSynonymsCK MB CFr SerPl ElphCategorychemistrySampleserumContainerRed-top tube (SST)UnitsN/ARef low22Ref high198Critical range7.2 N/A – 7.6 N/AFastingfalsePopulationadultSexallAge range18–65 yearsMethodelectrophoresisCPT82553Specimen volume5 mLStabilityRoom temperature: 4h, Refrigerated: 24h, Frozen: 7dHemolysis max500Lipemia max1000Icterus max500TAT4–24 hoursOrderroutine
## Why Might This Test Be Ordered?


Your healthcare provider may order this test if you have symptoms such as muscle pain, weakness, dark urine, or signs of kidney problems. It’s also sometimes used in cases of suspected muscle injury, such as from trauma, overexertion, or certain medical conditions.


## What Does Myoglobin Tell Us About Your Health?


Elevated levels of myoglobin in your blood can indicate muscle damage or breakdown. This can occur with conditions like rhabdomyolysis (a serious condition where muscle tissue breaks down rapidly), muscle injuries, or certain metabolic disorders.


## How Is This Test Performed?


A small blood sample is drawn from a vein in your arm. The sample is then processed and analyzed using electrophoresis, a technique that separates proteins based on their electrical charge.


## What Are Common Causes of Abnormal Results?


High myoglobin levels may be linked to muscle trauma, intense exercise, certain medications, or underlying conditions like myopathies or metabolic disorders. Low levels are less commonly reported but may occur in rare cases of muscle wasting or certain genetic disorders.


Reference range


Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.


## Clinical interpretation


How abnormal results are interpreted and what conditions they suggest.


Clinical Significance: Myoglobin Levels and Health Risks


## Short name


Myoglobin (Serum/Plasma Electrophoresis)


## Frequently asked questions
What are the typical reference ranges for this test?Reference ranges can vary by lab and may not be provided if the method or specimen type isn’t standardized. Your results will be interpreted by your healthcare provider based on your clinical situation.How soon after muscle injury or activity should I expect results?Results may take several days to a week, depending on lab processing times. Your provider will discuss timelines with you based on your test order.Can lifestyle changes affect my myoglobin levels?Extreme physical exertion or muscle damage can temporarily raise myoglobin levels. Avoiding strenuous activity before testing may help ensure more accurate results, but consult your provider for personalized advice.
## Sources
3
1. 1MedlinePlus — Laboratory TestsSource
2. 2Lab Tests OnlineSource
3. 3Mayo Clinic — Tests & ProceduresSource


Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.


This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.


If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.


Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy