Serum/plasma protein electrophoresis (qualitative)
This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or other disorders."]
Key facts at a glance
- LOINC
- 72562-2
- Short code
- CK MM CFr.DF SerPl Elph
- Synonyms
- CK MM CFr.DF SerPl Elph
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 22
- Ref high
- 198
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 82553
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins into five main zones: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins. Each zone contains different proteins that help your body function, including antibodies, enzymes, and transport proteins. Abnormal patterns may indicate conditions like inflammation, infections, or genetic disorders.
Why It’s Ordered
Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if tests suggest an issue with protein production or breakdown. It’s also used to monitor conditions like multiple myeloma, liver disease, or kidney problems.
Sample Collection
A blood sample is drawn from a vein, usually in your arm. You may feel a small pinch, but it shouldn’t cause significant discomfort. The blood is then sent to a lab for processing and analysis.
Preparation
No special preparation is needed, but avoid eating or drinking anything (except water) for 2–4 hours before the test if instructed. Inform your provider about any medications or supplements you’re taking.
Reference range
Adult males: 22-198 U/L; Females: 22-198 U/LN/A
No special preparation required. Inform provider of any chest pain or symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
Abnormal results may reveal conditions such as multiple myeloma (overproduction of abnormal proteins), liver disease (reduced albumin), or immune disorders (elevated gamma globulins). Low albumin could signal malnutrition or kidney issues.
How long will results take?
What if my results are abnormal?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy