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Serum or plasma protein electrophoresis with bromocresol purple staining

Published: August 9, 2026Updated: August 17, 2026

This test measures the distribution of different proteins in your blood, often used to check for conditions affecting protein levels or patterns, such as certain types of kidney disease or liver disorders.

Quick summary

["Helps identify abnormal protein patterns that may signal underlying health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2155-0
Short code
CK MM SerPl Elph-cCnc
Synonyms
CK MM SerPl Elph-cCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Protein electrophoresis separates blood proteins into fractions based on their size and electrical charge. Bromocresol purple staining highlights specific protein bands, helping to detect variations in protein concentration across different regions of the electrophoresis gel.

Common Uses and Conditions Monitored

This test is commonly used to diagnose or monitor conditions like multiple myeloma, certain types of kidney disease (e.g., nephrotic syndrome), liver diseases, and hereditary protein disorders. It may also be used as part of a general health evaluation or to assess protein metabolism.

Sample Collection and Preparation

Blood is drawn from a vein, typically in your arm. The sample is then processed to separate serum or plasma, which is sent to the lab for electrophoresis. No special preparation is needed, but fasting may be advised depending on the clinical context.

Interpreting Results

Results are interpreted by comparing the protein bands to reference patterns. Abnormal bands or shifts may indicate elevated or reduced levels of specific proteins, which can help guide diagnosis and treatment planning.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis (BCP)

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test if they suspect conditions affecting protein balance, such as kidney disease, liver disease, or certain cancers. It can also help monitor treatment progress for conditions like multiple myeloma or hereditary disorders.
What does an abnormal result mean?
An abnormal result may show unusual patterns of protein bands, which could signal conditions like protein loss in the urine (e.g., nephrotic syndrome), abnormal protein production (e.g., multiple myeloma), or metabolic disorders. Always discuss results with your healthcare provider.
How often should this test be repeated?
Frequency depends on your clinical condition. If you have a chronic illness or ongoing monitoring needs, your doctor may schedule follow-up tests at regular intervals, such as every few months or annually. Follow their guidance for the best plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy