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Clarithromycin (Serum/Plasma) Concentration Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of clarithromycin, an antibiotic, in your blood. It helps doctors check if your dose is working properly and if you’re responding to treatment.

Quick summary

["Clarithromycin levels help ensure your antibiotic is effective and avoid unnecessary side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73441-8
Short code
Clarithro ind plt IgG SerPl Ql FC
Synonyms
Clarithro ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’re taking clarithromycin (a medication like Biaxin) to treat or prevent bacterial infections, such as pneumonia, ear infections, or certain types of skin or urinary infections. It’s also used in cases where the infection is resistant to other antibiotics. Your doctor might also check levels if you’re taking clarithromycin long-term or have a condition that affects how your body processes drugs.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm or vein to draw a blood sample. It usually takes a few minutes. If you’re on a blood thinner, let your doctor know before the test.

What the Test Results Mean

The test result shows your current level of clarithromycin in your blood. This helps your doctor determine if your dose is too high, too low, or just right. For example, low levels might mean the antibiotic isn’t working well, while high levels could increase your risk of side effects like stomach upset or rash.

Possible Side Effects

Clarithromycin is generally well-tolerated, but some people may experience mild side effects like nausea, diarrhea, or stomach pain. Rarely, it can cause more serious reactions, such as liver problems or allergic reactions. If you notice unusual tiredness, yellowing of the skin/eyes, or severe rash, contact your doctor immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Clarithromycin Level

Frequently asked questions

What does clarithromycin do in the body?
Clarithromycin is a macrolide antibiotic that works by stopping the growth of bacteria. It’s effective against many types of bacteria, including some that cause respiratory infections, skin infections, and sexually transmitted infections. Your doctor may use this test to monitor how your body is handling the medication, especially if you have a condition like liver disease or kidney problems that can affect drug levels.
How often should I get this test?
The frequency of this test depends on your treatment plan. Your doctor may order it once during your initial treatment or periodically if you’re taking clarithromycin long-term. If you’re taking it for a short course (like a few weeks), you might only need it once or twice. If you’re on a long-term regimen, your doctor may check levels more frequently to adjust your dose as needed.
Can I drink alcohol before or after this test?
Yes, you can drink alcohol before the test, but avoid it for at least 24 hours after taking clarithromycin. Alcohol can affect how your body processes the medication, and it may also interact with clarithromycin, potentially causing side effects like stomach upset or dizziness. Always follow your doctor’s advice regarding alcohol use while on antibiotics.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy