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Clarithromycin Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of clarithromycin, an antibiotic, in your blood serum. It helps doctors check if your dose is working properly and if you’re responding well to treatment.

Quick summary

["Clarithromycin levels help ensure your antibiotic therapy is effective and avoid unnecessary side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43990-1
Short code
Clarithro Islt Slgr Mcbct AB 3.0
Synonyms
Clarithro Islt Slgr Mcbct AB 3.0
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking clarithromycin to treat or prevent bacterial infections, such as ear infections, respiratory infections, or certain types of skin infections. It may also be used to monitor long-term use or adjust your dose based on how your body processes the medication.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into a vein (usually in your arm) to draw a blood sample. The process is quick and typically causes only minor discomfort. If you’re on blood thinners or have a history of bleeding disorders, let your doctor know before the test.

What the Results Mean

Results are compared to a reference range that varies by lab and individual factors like age, health, and medication use. A therapeutic range ensures the antibiotic is effective without causing harmful side effects. Your doctor will interpret the results in the context of your medical history and treatment plan.

Common Reasons for Abnormal Results

Low levels might indicate the antibiotic isn’t working as expected, poor absorption, or drug interactions. High levels could suggest kidney issues, improper dosing, or rare allergic reactions. Always discuss any concerns with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Clarithromycin Levels

Frequently asked questions

Why do I need this test if I’m already taking clarithromycin?
Your doctor may order this test to confirm the antibiotic is reaching the right levels in your blood, especially if you’re taking it for a serious infection, adjusting your dose, or experiencing symptoms that suggest the medication isn’t working.
What are the typical side effects of clarithromycin, and how might this test help?
Common side effects include nausea, diarrhea, or stomach pain. If you’re experiencing severe or persistent symptoms, this test can help determine if the antibiotic is too low to work effectively or if you need a dose adjustment. It also helps identify rare issues like liver problems or allergic reactions.
Can food or other medications affect my clarithromycin levels?
Yes, certain foods, medications (like antacids or other antibiotics), or health conditions (like liver/kidney disease) can alter how your body absorbs or processes clarithromycin. Your doctor may recommend timing your dose or avoiding certain interactions to keep levels stable.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy