Lymph Node Biopsy for Pathological Examination (Cleft Lymph Node Specimen)
This test involves examining a sample of lymph node tissue removed during surgery to check for abnormalities such as infection, inflammation, or cancer. The tissue is analyzed under a microscope by a pathologist.
["A lymph node biopsy helps diagnose conditions affecting your immune system or lymph system."]
Key facts at a glance
- LOINC
- 30418-8
- Short code
- Cleft Lymphs # Bld
- Synonyms
- Cleft Lymphs # Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may recommend a lymph node biopsy if they suspect an infection, such as lymphadenitis, or an underlying condition like lymphoma, metastatic cancer, or an autoimmune disorder. Symptoms like swollen, painful, or persistent lymph nodes may prompt this test.
What to Expect Before the Test
You will likely be given a local anesthetic to numb the area where the lymph node is removed. The procedure is usually done in a hospital or clinic and may take a few minutes. Recovery is quick, but you may experience mild soreness afterward.
During the Test
A surgeon or specialist will remove a small piece of the lymph node using a needle or surgical incision. The tissue is then sent to a lab for microscopic examination by a pathologist.
After the Test
You can typically go home the same day or the next day, depending on the procedure. Follow your doctor’s instructions for post-procedure care, such as managing pain or keeping the incision clean.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for identifying the cause of lymph node enlargement or dysfunction. Pathologists analyze cellular structures to determine whether the issue is benign (non-cancerous), inflammatory, or malignant (cancerous), guiding treatment decisions.
Short name
Lymph Node Pathology
Frequently asked questions
What does a lymph node biopsy involve?
How long does it take to get results from a lymph node biopsy?
Can I eat or drink before a lymph node biopsy?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy