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Lymph Node Fluid Protein Electrophoresis (Manual)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in fluid collected from a lymph node biopsy, often used to diagnose conditions like lymphoma or infections.

Quick summary

["Protein electrophoresis helps identify abnormal protein patterns that may signal cancer or immune system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15197-7
Short code
Cleft Lymphs NFr Bld Manual
Synonyms
Cleft Lymphs NFr Bld Manual
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like swollen lymph nodes, unexplained weight loss, fever, or night sweats. It helps determine whether the fluid contains abnormal cells, which could indicate lymphoma, infections, or other conditions affecting your immune system.

How the Test Is Performed

A small amount of fluid is collected from a lymph node during a biopsy. The fluid is then processed and analyzed using electrophoresis, a technique that separates proteins based on size and charge. This allows for detailed examination of protein composition.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to avoid certain medications or foods that could interfere with results. Your doctor will explain any restrictions and provide instructions for the day of the procedure.

What to Expect During the Test

The procedure involves a local anesthetic to numb the area, followed by a small incision to collect fluid. The fluid is then sent to a lab for analysis. The process usually takes a few minutes and may cause mild discomfort.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns detected in lymph fluid can help diagnose conditions such as lymphoma, infections (like tuberculosis), or other immune-related disorders. For example, certain proteins may indicate the presence of malignant cells, while others may suggest inflammation or infection.

Short name

Lymph Fluid Protein Profile

Frequently asked questions

What does the test measure?
This test measures the protein composition in lymph fluid, including albumin, globulins, and other proteins. Electrophoresis helps identify any unusual patterns that may point to underlying health issues.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your doctor will contact you with the findings once they are ready.
Can I eat or drink before the test?
You can usually eat and drink normally before the test unless instructed otherwise by your doctor. Avoid medications that may affect protein levels if your provider advises it.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy