: Clinical Signs of Congenital Syphilis
: This test documents whether an infant shows physical signs consistent with congenital syphilis, a syphilis infection passed from mother to baby during pregnancy or birth.
: Recognizing physical signs of congenital syphilis helps clinicians decide on further testing and early treatment.
Key facts at a glance
- LOINC
- 75193-3
- Short code
- CLINICALSIGNSOFCONGENITALSYPHILIS
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cdc-cs
- CPT
- 86592
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What This Assessment Is
: Congenital syphilis occurs when the bacterium that causes syphilis is transmitted from a pregnant person to the fetus. This entry captures the clinical (physical) signs a clinician observes during examination of the infant, rather than a laboratory measurement.
: Signs Clinicians Look For
: Healthcare providers examine the baby for findings that may include rash, jaundice, nasal discharge, bone or joint changes, enlarged liver or spleen, and other abnormalities. Because signs can be subtle or absent at birth, a thorough physical exam is important.
: How It Fits With Other Tests
: Physical findings are considered together with the mother's syphilis test results and the infant's own blood tests, such as serology and other laboratory studies. No single sign or test confirms the diagnosis on its own.
: What Happens Next
: If signs are present or risk is high, the care team may recommend additional testing and treatment. Early identification and treatment generally lead to better outcomes for the infant.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
: Documenting clinical signs of congenital syphilis supports timely diagnosis and treatment. Because many affected infants appear normal at birth, this assessment is used alongside maternal history and laboratory testing to guide management.
Short name
: Congenital Syphilis Signs
Frequently asked questions
: Does a normal physical exam rule out congenital syphilis?
: Is this the same as a blood test for syphilis?
: Why is early recognition important?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy