Syphilis serology with stage-specific interpretation during pregnancy
This test measures antibodies to syphilis in your blood to determine your stage of infection during pregnancy, helping guide treatment and monitoring.
Your syphilis test helps doctors determine the best care for you and your baby.
Key facts at a glance
- LOINC
- 75180-0
- Short code
- CLINICALSTAGEOFSYPHILISDURINGPREGNANCY
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cdc-cs
- CPT
- 86592
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done During Pregnancy
Syphilis can affect both you and your baby if left untreated. This test helps healthcare providers identify the stage of infection—early, late, or latent—to ensure appropriate treatment and prevent complications. Early detection allows for timely treatment with antibiotics, which can prevent serious harm to your baby.
What the Test Measures
The test detects antibodies (RPR or VDRL) produced by your immune system in response to syphilis bacteria. These antibodies help determine whether you have an active infection and its stage. Some tests may also include confirmatory assays (e.g., FTA-ABS) to confirm the diagnosis.
How the Test Is Performed
A blood sample is taken from a vein in your arm. The sample is sent to a lab for testing. Results are typically reported as a titer (a measure of antibody level) and stage classification (e.g., early, late, or latent syphilis).
What the Results Mean
Results are interpreted in the context of your medical history, symptoms, and other factors. Early syphilis shows lower antibody levels, while latent or late syphilis may indicate higher titers. Your healthcare provider will discuss the findings with you and recommend follow-up care.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Syphilis serology (pregnancy staging)
Frequently asked questions
How long will it take to get my results?
What if I have false-positive results?
Can I treat syphilis at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy