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C-reactive protein, serum/plasma concentration (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP) in your blood. CRP is produced by your liver in response to inflammation, helping your body fight infections or injury.

Quick summary

["CRP helps track inflammation, which can signal underlying health issues like infections, autoimmune diseases, or heart conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107053-1
Short code
CLL MRD Bld FC
Synonyms
CLL MRD Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is CRP Used For?

CRP is often checked to monitor inflammation in conditions like infections, arthritis, or after surgery. High levels may indicate an active inflammatory process, while low levels suggest reduced inflammation.

Why Might Your Doctor Order This Test?

Your doctor may order hs-CRP to assess risk for heart disease, evaluate symptoms of inflammation, or monitor treatment progress for conditions like rheumatoid arthritis or lupus.

What Does a High or Low CRP Level Mean?

Elevated CRP levels often point to inflammation, but they can also be normal in some infections or after minor injuries. Low CRP may mean your body isn’t responding to inflammation, though other factors could be at play.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to measure CRP levels using a sensitive lab method that detects even small amounts.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

Why do some people get this test before surgery?
High-sensitivity CRP helps doctors evaluate the risk of complications like heart attacks or strokes before procedures, especially in patients with risk factors like high blood pressure or diabetes.
Can CRP levels change with diet or exercise?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Reducing inflammation through healthy habits may lower CRP over time, but results depend on overall health and medical conditions.
What if my CRP is consistently high?
If your CRP remains elevated, your doctor may investigate causes like infections, autoimmune diseases, or other health conditions. They could recommend lifestyle changes, medications, or further testing to address the underlying issue.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy