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Clofazimine Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of clofazimine, a medication used to treat certain skin and systemic infections, in your blood serum.

Quick summary

["Knowing your clofazimine levels helps doctors monitor your treatment effectiveness and adjust your dose safely."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43986-9
Short code
Clofazimine Islt Slgr Mcbct AB 2.0
Synonyms
Clofazimine Islt Slgr Mcbct AB 2.0
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Clofazimine is a powerful antibiotic and anti-inflammatory drug primarily prescribed for conditions like leprosy. Your body processes it differently based on factors like metabolism, diet, and other medications you take. Regular monitoring helps prevent side effects, such as skin discoloration or liver issues, and ensures the drug remains effective against infections.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or vein to draw a blood sample. The process is quick and usually painless. If you’re on other medications, let your healthcare provider know before the test.

What the Results Mean

Your results will show the concentration of clofazimine in your blood. While reference ranges vary by lab, low levels may indicate the drug isn’t working well, while high levels could signal side effects or improper dosing. Your doctor will interpret these results in the context of your medical history and treatment plan.

Common Reasons for This Test

Doctors order this test to check if clofazimine is working as intended in treating infections like leprosy, to adjust your dose if needed, or to monitor for potential side effects. It’s also used in research or specialized treatment protocols.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Clofazimine Level

Frequently asked questions

What could cause abnormal results?
Abnormally low clofazimine levels might mean your body isn’t absorbing or metabolizing the drug properly, which could require a higher dose or alternative treatment. High levels could suggest liver issues, drug interactions, or improper dosing. Always discuss any concerns with your healthcare provider.
How often should I get this test?
Your doctor will determine the frequency based on your treatment plan, but it’s often done periodically (e.g., every few weeks or months) to ensure your levels stay within a safe and effective range.
Can diet or other medications affect this test?
Yes, certain foods (like high-fat meals) or other medications (e.g., rifampin, antacids) can influence clofazimine levels. Always inform your healthcare provider about all medications, supplements, and dietary habits before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy