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Clomipramine Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of clomipramine, a medication used to treat depression, anxiety, and other mental health conditions, in your blood serum.

Quick summary

["Understanding your clomipramine levels helps ensure your medication is working safely and effectively."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16625-6
Short code
clomiPRAMINE Mlk-mCnc
Synonyms
clomiPRAMINE Mlk-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to monitor your response to clomipramine therapy, check for drug levels that are too high or too low, or assess potential side effects. It’s often done during treatment adjustments or if you experience unusual symptoms.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The process is quick and usually painless. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are used to guide your treatment plan. Low levels might indicate the medication isn’t working as intended, while high levels could signal toxicity or improper dosing. Your provider will interpret results in the context of your symptoms and medical history.

Common Reasons for Testing

This test is commonly ordered if you’re taking clomipramine long-term, if you’re experiencing mood swings, fatigue, or other unusual symptoms, or if your provider wants to ensure your medication levels are within a safe range.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clomipramine is a tricyclic antidepressant used to manage depression, anxiety disorders, and other conditions. Maintaining appropriate blood levels is critical to balance efficacy and safety. Abnormally high levels may cause side effects like dizziness, dry mouth, or irregular heartbeat, while very low levels may reduce the drug’s effectiveness. Regular monitoring helps prevent these issues.

Short name

Serum Clomipramine Level

Frequently asked questions

How often should I expect this test if I’m taking clomipramine?
The frequency depends on your treatment plan. Some patients get tested weekly or monthly during initial adjustments, while others may have less frequent follow-ups once stable. Your provider will specify the schedule based on your needs.
What symptoms might indicate my clomipramine levels are too high?
Signs of elevated clomipramine levels can include dizziness, confusion, rapid heartbeat, nausea, or severe fatigue. If you experience these symptoms, contact your healthcare provider immediately.
Can I stop taking clomipramine before my next test?
No, it’s important to follow your provider’s instructions. Stopping the medication abruptly can be dangerous, and skipping tests may lead to incorrect conclusions about your health. Always discuss any changes with your provider first.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy